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Methodology of organic synthesis

ВБ.4.01

Вибіркова дисципліна для ОП

Second

2021/2022

2 Semester

6

P1. Knowledge to understand scientific concepts and modern theories of chemistry, as well as the fundamentals of related sciences. P2. Deeply understand the basic facts, concepts, principles and theories related to the subject area... P4. Synthesize chemical compounds with specified properties, analyze them and assess compliance with specified requirements. P6. Know the methodology and organization of scientific research. P9. Collect, evaluate, and analyze the data wanted to solve complex chemistry problems using appropriate data methods and tools. P10. Plan, organize and conduct experimental research in chemistry using modern equipment, competently process their results and draw sound conclusions. P15. Possession of the general methodology of scientific research.

Full-time form

1. Know organic chemistry at the bachelor's degree in Chemistry. 2. Have skills in writing organic reactions. 3. Have an idea of stereochemistryat the bachelor's degree in Chemistry. 4. Have the skills to write the mechanisms of organic reactions at the bachelor's degree in Chemistry.

Methods of organic synthesis that allow the transformation of functional groups and the construction of CC bonds, the mechanisms of reactions used, their stereochemical features. Methods of organic synthesis in terms of solving its strategic tasks (choosing the optimal scheme for the synthesis of complex organic compounds), as well as tactical tasks (choice of reagents and conditions for a particular stage of synthesis). Isohypsic and non-isogypsic transformations of functional groups, chemical properties of carbanions and organometallic compounds, reactions of carbonyl compounds, pericyclic reactions, methods of formation of carbocyclic systems.

1) Modern methods of organic synthesis: textbook for students. chemical f-tu / O.O. Grygorenko, O.V. Shablykina – K.: VOC "Kyiv University", 2020. – 572 p. 2) W.A. Smith., A.F. Bochkov, R. Caple. Organic Synthesis – the Science behind the Art. Cambridge, 1998. – 477 p. 3) M. Smith. Organic Synthesis. 3rd Ed. Academic Press, 2011. – 1534 p. 4) March's Advanced Organic Chemistry:  Reactions, Mechanisms and Structure, 5th ed by M. B. Smith and J. March. – Wiley Interscience:  New York. 2001. – 2112 p.

Practical classes, lectures

Evaluation is carried out on a 100-point system. Current control - homework, practical work in the classroom, tests (maximum 60 points), exam (maximum 40 points)

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