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Histophysiology of the neuroendocrine system

Вибіркова дисципліна для ОП

Second

2021/2022

3 Semester

5

PR2. Use libraries, information databases, Internet resources to search for the necessary information. PR6. Analyze biological phenomena and processes at the molecular, cellular, organismal, population-species and biosphere levels in terms of basic general scientific knowledge, as well as using special modern research methods. PR7. Describe and analyze the principles of structural and functional organization, mechanisms of regulation and adaptation of organisms to the influence of various factors. PR11. To carry out statistical processing, analysis and generalization of the received experimental data with use of software and modern information technologies. PR 19. Solve scientific-theoretical, research and applied problems of biology by appropriate methods.

Full-time form

1. Know the histogenesis and submicroscopic structure of the elements of the glandular epithelium, anatomy, basics of biochemistry and physiology of endocrine organs. 2. Be able to use microscopic instruments to distinguish between different types of glandular cells of the endocrine system at the cyto- and histological level. 3. To have basic skills of making histological preparation of endocrine organs and the ability to work with a light microscope.

Discipline is the basis for obtaining a holistic view of the structural and functional organization of the neuroendocrine system and the principle of regulation peripheral endocrine glands. The learning process compares the main stages of the evolution of the neurosecretory system in invertebrates and vertebrates. Cytoarchitectonics of mammalian and human hypothalamus with characteristics of neurosecretory nuclei, hypothalamic tracts, medial elevation and pituitary gland, features of the structure of the portal circulatory system between the hypothalamus and pituitary gland are analyzed in detail. The histostructure of endocrine glands and the reasons of development of the most widespread pathologies, features of morpho- and pathogenesis of endocrine glands and their consequences for the hormonal status of the organism. Pierce's concept of the APUD system on the example of the characteristics of gastrointestinal endocrinocytes is considered.

1. Endocrinology. Textbook / Ed. A.S. Yefimova. - К .: Вища школа, 2004. - 494 с. 2. Endocrinology. Textbook / Ed. P.M. Bodnara. - Vinnytsia: Nova Kniga, 2007. - 344 p. 3. Bodnar PM,. Mikhalchishin GP, ​​Komisarenko YI, Endocrinology. Textbook / Ed .: Prof. P.M. Bodnar. - Vinnytsia: New book, 2010. - 464p. 4. Ostapchenko LI Hormonal regulation of metabolism and functions in the human body. - Kyiv: Ukrainian Orthodox Church “Kyiv University”, 2003. - 154 p. 5. Ostapchenko LI and others. Biochemistry. - Kyiv: Ukrainian Orthodox Church “Kyiv University”, 2012. - 796 p

Lectures, independent work, laboratory and practical classes.

- semester assessment: 1. Modular test 1 (written, open-ended questions and tests) RN 1.1, 1.2, 2.1, 2.2 - 20 points / 10 points. 2. Modular test 2 (written, open-ended questions and tests) RN 1.1 - 1.3, 2.1, 2.2. - 30 points / 15 points. 3. Assessment of knowledge of histological preparations of the nuclei of the hypothalamus, pituitary gland, pineal gland, thymus and peripheral endocrine glands (tested by the teacher using a light microscope and an oral description of the histological structure of the drug) PH 1.1 - 4.1 - 5 points / 2.5 points. 4. Evaluation of the implementation of practical tasks RN 2.1 - 4.1 - 5 points / 2.5 points. - final assessment: in the form of an exam

Ukrainian