Infopaket

Design of cancer immunotherapy

Вибіркова дисципліна для ОП

Second

2021/2022

1 Trimester

4

PR3. Carry out coordinated work for the result in the team, taking into account public, state and industrial interests. PR 13. Adhere to the basic rules of biological ethics, biosafety, biosecurity, assess the risks of the latest biological, biotechnological and biomedical methods and technologies, identify potentially dangerous organisms or production processes that may pose a threat of emergencies. PR14. Adhere to the norms of academic integrity in the study and conduct of scientific activities, know the basic legal norms for the protection of intellectual property. PR 19. Solve scientific-theoretical, research and applied problems of biology by appropriate methods. PR 31. Be able to use existing, develop and implement new research methods and technologies to solve specific scientific-theoretical and / or applied problem in immunology.

Full-time form

1. Successful mastering of scientific-theoretical and practical material of academic disciplines taught to students of educational level "Bachelor" and special disciplines such as "Cellular Immunity", "Immunochemistry", "Immunogenetics", "Antitumor Immunity", "Immunopathology", "Natural resistance" and others. 2. Knowledge of the theoretical foundations of immunology, biochemistry, human and animal physiology, genetics, cytology and histology, microbiology, virology, biophysics, etc. 3. Knowledge of the basic principles of basic biological methods.

The discipline "Design of cancer immunotherapy" covers the issues of different immunotherapeutic approaches to the activation of specific antitumor immunity in the formation / presence of tumor-associated immunosuppression. In particular, the issues of the antigenic composition of tumor cells, the interaction of the tumor and the immune system, different approaches to the design of antitumor immunotherapeutic agents are considered; information on the classification of antitumor immunotherapy, the main types of antitumor vaccines and their mechanism of action; data on the effectiveness of clinical use of anticancer vaccines and other immunotherapeutic agents.

1. Chekhun VF edited by. Oncology. Selected Lectures for Students and Physicians, 2010, 768 p. 2. Vershigora A.Yu., Pasteur E.U., Kolybo DV, Pozur V.K., Vikhot ME, Mikhalsky L.O., Shvets Yu.V., Kholodna L.S., Моложава О.С. Immunology. - Kyiv: Higher school, 2005. - 599 p. 3. Chekhun VF, Lisovenko GS, Potebnya GP Anticancer vaccines: finding the optimal solution, 2013, 109 p. 4. Yalkut SI, Potebnya GP Tumor biotherapy. 2010, 472 p. 5. Grinevich Yu.Ya. edited by. Specific immunotherapy in oncology, 2008, 415 p.

Lectures and laboratory work, independent work

- semester assessment: 1. Modular test 1: PH 1.1- 2.3 - 10 points / 5 points 2. Modular test work 2: PH 1.1 - 2.3 - 10 points / 5 points 3. Summary: PH 4.1 - 10 points / 5 points 4. Laboratory work: RN 2.1 - 2.3 - 30 points / 15 points for each - final assessment: in the form of an exam

Ukrainian