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Mechanisms of signal transduction in cells of the immune system

Вибіркова дисципліна для ОП

Second

2021/2022

2 Semester

5

PR2. Use libraries, information databases, Internet resources to search for the necessary information. PR5. Analyze and evaluate the impact of biology on the development of society. PR12. Use innovative approaches to solve complex problems of biology under uncertain conditions and requirements. PR 20. On the basis of in-depth knowledge of natural sciences to form an idea of ​​the laws of individual and historical development of biological systems at different levels of organization, the role of systemic processes in their formation, functioning and plasticity, features of their cooperative interaction. PR32. Be able to form a system of knowledge for the interpretation of new data on the structure and function of the immune system and its components in different physiological states based on in-depth knowledge of the disciplines of vocational training

Full-time form

1. Successful mastering of scientific-theoretical and practical material of academic disciplines taught to students of educational level "Bachelor" 2. Know the theoretical foundations of immunology, biochemistry, human and animal physiology, genetics, cytology and histology, microbiology, virology, biophysics, etc. 3. Possess basic skills of basic biological method

The discipline is a basic discipline that covers the expression, structure and functions of the main classes of receptors of immune system cells. Emphasis is placed on molecular and cellular mechanisms of information transmission in immune system cells, principles of modular structure of signal cascade components, role of posttranslational modifications in signal transduction, principles of signal modules organization in signal networks, multilevel regulation of cell signaling systems. pathological conditions, components of signaling networks as diagnostic markers and targets for targeted therapy of leukemia and lymphoma.

1. Vershigora A.Yu., Pasteur E.U., Kolybo D.V. etc. Immunology. Textbook. K .: Publishing and Printing Center "Kyiv University", 2011. - 911 p. 2. Kian-Huat Lim and Louis M. Staudt. Toll-Like Receptor Signaling. Cold Spring Harb Perspect Biol 2013; doi: 10.1101 / cshperspect.a011247 3. E. Nigel Wardle. Guide to Signal Pathways in Immune Cells, Humana Press, London, UK, 2009. 415 p.

Lectures and laboratory work, independent work.

- semester assessment: 1. Modular test 1: PH 1.1 - 2.4-20 points / 10 points 2. Modular test work 2: PH 1.1 - 2.4 - 20 points / 10 points 3. Abstract and presentation: RN 3.1, 4.2 - 8 points / 4 points 4. Laboratory works: RN 2.1- 2.4. - 12 points / 6 points - final assessment: in the form of an exam

Ukrainian