Clinical pathophysiology and pathogenetic therapy
Course: Medicine (the Ukrainian language of instruction)
Structural unit: Biology And Medicine Institute Science Educational Center
Title
Clinical pathophysiology and pathogenetic therapy
Code
Module type
Вибіркова дисципліна для ОП
Educational cycle
Second
Year of study when the component is delivered
2025/2026
Semester/trimester when the component is delivered
11 Semester
Number of ECTS credits allocated
3
Learning outcomes
To identify and identify the leading clinical symptoms and syndromes (according to list 1); according to standard methods, using preliminary data from the patient's history, examination data, knowledge about the person, his organs and systems, to establish a preliminary clinical diagnosis of the disease (according to list 2)
To collect information about the patient's general condition, to assess the patient's psychomotor and physical development, the state of the body's organs and systems, to evaluate information on the diagnosis based on the results of laboratory and instrumental studies (according to list 4).
To prescribe and analyze additional (mandatory and optional) examination methods (laboratory, functional and/or instrumental) (according to list 4), patients with diseases of organs and body systems for differential diagnosis of diseases (according to list 2)
Form of study
Prerequisites and co-requisites
Successful mastery of the academic disciplines "Biological and bioorganic chemistry", "Physiology", "Life safety, the basics of bioethics and biosafety", "Radiology", "Pathophysiology", "Pharmacology and medical prescription", "Propaedeutics of internal medicine", "General surgery", "Internal medicine", "Obstetrics and gynecology", "Neurology", "Psychiatry and narcology", "Clinical surgery with a course of anesthesiology and resuscitation".
2. The ability to independently apply knowledge from fundamental and clinical disciplines to solve specific scientific and practical problems; work with scientific and scientific-methodological literature.
3. Possession of elementary skills of systems analysis.
Course content
The course covers key aspects of violations of the volemic status, principles of volume correction, pathophysiology of hemotransfusions, shock and sepsis. The mechanisms of development of traumatic injuries, physiological changes during local and general anesthesia are considered. The main part of the classes is focused on the syndromic approach to the diagnosis of pathologies, including the analysis of the results of physical, laboratory and instrumental examination methods, using modern algorithms of differential diagnostic search. A separate block of classes is devoted to the tactics of managing patients (endocrine, therapeutic and surgical profile) in accordance with modern clinical guidelines and standards with their analysis through the prism of understanding the pathogenesis of the diseases under consideration. The discipline forms in students a deep understanding of the mechanisms of development of the most common diseases and conditions, as well as the skills of pathogenetically based therapy and prevention in accordance with modern data.
Recommended or required reading and other learning resources/tools
Main:
1. State Expert Center of the Ministry of Health of Ukraine, https://www.dec.gov.ua
2. “Pathophysiology” for students of the educational and professional program “Medicine”
of the educational level “Master” / textbook // Kovalchuk O. I., Mnevets R. O.,
Yatsyna O. I., Falaleeva T. M., Smirnov O. E. // Kyiv, 2023. – 447 p.
3. National Library of Medicine, https://pubmed.ncbi.nlm.nih.gov/
Additional:
1. Portal https://empendium.com/ua/
10. Additional resources:
1. DO “Testing Center”: [official site]. – URL: testcentr.org.ua
Planned learning activities and teaching methods
semester assessment:
1. Intermediate control No. 1: РН 1.1, 2.1 – 2.5 – 10 points / 5 points
2. Intermediate control No. 2: РН 1.2, 2.1 – 2.5 – 10 points / 5 points
3. Intermediate control No. 3: РН 1.3, 2.1 – 2.5 – 10 points / 5 points
4. Assessment for work in practical classes: РН 1.1 – 2.5 – 25 points / 12.5 points
5. Assessment for additional work: РН 1.6, 3.1, 4.1 – 15 points / 7.5 points
6. Final modular test: РН 1.1 – 4.1 – 30 points / 15 points - final assessment: in the form of credit
Assessment methods and criteria
Final module test, midterm test, assessment of work in practical classes, completion of additional work
Language of instruction
ukrainian
Lecturers
This discipline is taught by the following teachers
Ruslan
Olexandrovych
Mnevets
Department of Pediatrics, Obstetrics and Gynecology
Biology And Medicine Institute Science Educational Center
Biology And Medicine Institute Science Educational Center
Departments
The following departments are involved in teaching the above discipline
Department of Pediatrics, Obstetrics and Gynecology
Biology And Medicine Institute Science Educational Center