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Macromolecules of bioorganic nature. Part IІ.

Вибіркова дисципліна для ОП

First

2025/2026

8 Semester

3

PR06. Apply models, methods and data of physics, chemistry, ecology, mathematics in the process of learning and ensuring professional activity. PR08. Know and understand the basic terms, concepts, theories and laws in the field of biological sciences and at the border of subject areas. PR11. Understand the structural organization of biological systems at the molecular level. PR19. Apply in practical activities methods for determining the structural and functional characteristics of biological systems at different levels of organization PR24. Analyze the physicochemical properties and functional role of biological macromolecules and molecular complexes of living organisms, the nature of their interaction with ions, molecules and radicals, their structure and energetics of processes.

External form

1. Successful mastery of the academic disciplines "Bioorganic Chemistry", "General Cytology", "Biochemistry", "Molecular Biology", "Biophysics". 2. Ability to independently apply knowledge of organic and bioorganic chemistry, molecular biology, biochemistry, general genetics and other academic disciplines to solve specific scientific and practical problems; work with scientific and scientific methodological literature. 3. Possession of basic skills of systems analysis.

The academic discipline "Macromolecules of Bioorganic Nature (Part 2)" introduces students to current ideas about the structure, physicochemical properties, and molecular biological features of lipids. In the context of the discipline, the various functions of lipids in living organisms are also considered: fats, which are a form of energy storage, phospholipids and steroids, which are part of biological membranes, other lipids that are contained in cells in smaller quantities and can be coenzymes, light-absorbing pigments, electron carriers, hormones, secondary mediators during intracellular signal transmission, hydrophobic "anchors" that hold proteins near membranes, chaperones that promote protein folding, emulsifiers in the gastrointestinal tract. Special attention is paid to the unique structural and functional characteristics of lipids, which make them the main elements of all cell membranes. The discipline provides modern insights into the molecular biological features of metabolic processes characteristic of lipids in normal and pathological conditions, as well as the conditions of transport and their participation in the development of atherosclerosis and diabetes.

1. Nelson D.L., Cox M.M. Lehninger Principles of Biochemistry. – New York: W.Y. Freeman and Comp; 8-th edition- 2021. – 1248 p. 2. Gurr M.I., Harwood J.L., Frayn K.N., Murphy D.J., Michell R.H. Lipids: Biochemistry, Biotechnology and Health, 6th Edition.– Wiley-Blackwell. – 2016.– 448 p. 3. Neale Ridgway, Roger McLeod. Biochemistry of Lipids, Lipoproteins and Membranes. New Comprehensive Biochemistry. 6-th ed.–Elsevier Sc.Рubl., Amsterdam. – 2016.– 599 p. 4. Vance D.E., VanceJ.E. Biochemistry of Lipids, Lipoproteins and Membranes. New Comprehensive Biochemistry. –ElsevierSc.Рubl., NewYork. – 2008. – 610p. 5. Gunstone F.D., Harwood J.L., Dijkstra A.J. The Lipid Handbook with CD-ROM. – CRC Press; 3-th edition. – 2007. – 1470 p.

Lectures, independent work

Semester assessment: Modular control work 1 (remote) – RN 1.1-3.1 – 30 points/ 15 points Modular control work 2 – RN 1.1-3.1 – 30 points/ 15 points Final evaluation (semester control): in the form of an exam