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The evolution of dangerous human viruses

Вибіркова дисципліна для ОП

Second

2023/2024

2 Semester

5

PRO3. To carry out coordinated work for the result in the team, taking into account public, state and industrial interests. PRO5. Analyze and evaluate the impact of biological achievements on the development of society. PRO9. Plan research, choose effective research methods and their material support. PR 11. Conduct statistical processing, analysis and generalization of experimental data using software and modern information technologies. PR 13. To adhere to the basic rules of biological ethics, biosafety, biosecurity, to assess the risks of using the latest biological, biotechnological and biomedical methods and technologies, to identify potentially dangerous organisms or production processes that may pose a threat of emergency situations.

External form

1. Successful mastery of the disciplines "Virology", "Safety principles in the virology laboratory", "Identification of viruses", "Genetics of viruses", "Fundamentals of viral carcinogenesis", "Antiviral immunity", "Human and animal viruses". 2. be able to independently apply the classification of human and animal viruses, the characteristics and taxonomic position of the main DNA- and RNA-containing viruses, the identification of representatives of different types of viruses, knowledge of general virology and other disciplines to solve specific scientific and practical problems, work with scientific and scientific-methodical literature. 3. Possess basic skills of system analysis.

The discipline "Evolution of Dangerous Human Viruses" is a component of the educational program of professional training of specialists of the educational level "Master". The discipline is a free choice of the student. The discipline is designed to form a system of abilities and skills in the evolution of viruses, conditions and mechanisms of evolutionary changes in populations of human and animal viruses, bacterial viruses, etc. An important place is given to the issues of genetics and molecular biology of viruses as criteria and factors of evolution rate, methods of micro- and macroevolution, hypotheses of the origin and evolution of viruses, along with methods of analysis and characterization of viral genomes and amino acid sequences, genetic analysis of viral populations and the dynamics of their changes, methods of phylogenetic analysis and construction of phylogenetic trees. The knowledge gained can be applied both in research in related sciences and in interdisciplinary projects that require knowledge of this discipline.

1. Wortel MT, Agashe D, Bailey SF, Bank C, Bisschop K, Blankers T, et al. Toward evolutionary predictions: current promises and challenges. Evol Appl (2023) 16:3-21. doi: 10.1111/eva.13513 2. Flint S. J. Principles of Virology: in 2 vols. - 4th ed. Y., 2015. 3. Moelling K. Viruses more friend than foes / K. Moelling. - World Scientific Publishing Co. Pte. Ltd, 2015. 4. URL : https://talk.ictvonline.org/ictv-reports/ictv_online_report/introduction. 5. Budzanivska I.G., Shevchenko TP, Korotieieva G.V., Molchanets O.V., Kharina AV, Kompanets TA, Andriychuk OM, Shevchenko OV, Kondratiuk OA Virology. Textbook. 309 с. 2019. 6. Polishchuk VP, Budzanivska IG, Shevchenko TP, Andriychuk OM, Kompanets TA, Kondratiuk AA, Korotieieva GV, Molchanets OV, Kharina AV, Shevchenko OV Virology. Study guide for laboratory classes. 242с. 2018. 7. A.J. Cann. Molecular Virology. London, Academic Press, 2001.-395 pp.

Lecture, laboratory work, independent work

- semester assessment: 1. Module control work (test) - PH 1.1, 1.2, 3.1, 4.1 - 60 points/ 30 points 2. Laboratory work - PH 2.1, 2.2, 2.3 - 40 points / 20 points - Final assessment: in the form of a test

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