Infopaket

Viruses as vector systems

Вибіркова дисципліна для ОП

Second

2023/2024

2 Semester

5

PR1. Know the state and foreign languages ​​at a level sufficient for communication on professional issues and presentation of the results of their own research. PR8. Apply during research knowledge of the peculiarities of the development of modern biological science, the basic methodological principles of scientific research, methodological and methodological tools for conducting research in specialization. PR9. Plan research, choose effective research methods and their material support. PR14. Adhere to the norms of academic integrity in the study and conduct of scientific activities, know the basic legal norms for the protection of intellectual property. PR18. Model objects and processes in living organisms and their components using mathematical methods and information technology.

External form

1. Successful mastering of the courses "Virology", "Molecular Biology", "Biotechnology", "Genetics of Viruses" and "Molecular Biology of Viruses". 2. Ability to apply knowledge and skills in the field of virology and molecular genetics, acquired during previous training, to search and analyze the scientific literature. 3. Possession of skills of abstract thinking, analysis and synthesis.

The discipline covers the basic principles of using viruses, or their fragments, to transfer recombinant DNA into the appropriate cell. The discipline considers various approaches to creating vectors for nucleic acid cloning and obtaining recombinant proteins based on genomes of viruses of microorganisms (bacteriophages), invertebrates and vertebrates and humans, including hybrid constructs (cosmids, phagemids, fazmids, their applications, etc.) and especially scientific and theoretical bases of practical use of vectors on the basis of human viruses for DNA therapy and DNA vaccination are laid.

1. Kompanets T.A. Viruses as vectors (a course of lectures for students of the Faculty of Biology). – M.: Phytosociocenter, 2007. 2. Viral vectors for gene therapy: Methods and protocols / Ed. by Machida C.A. - New Jersey: Humana Press, 2003. 3. Viral vectors: fundamental science and gene therapy / Ed. by Cid-Arregui A., Garcia-Carranca. – Natick: Eaton publishing, 2000.

Lecture, laboratory work, independent work.

- semester assessment: 1. Modular test 1 (remote) - PH 1.1 - 10 points / 5 points 2. Modular test 2 (remote) - PH 1.2, 2.1, 2.2 - 30 points / 15 points 3. Preparation of the abstract / report (remotely) - РН 1.1, 2.2, 3.1, 4.1 –10 points / 5 points 4. Oral answers / additions - РН 1.1,2.2, 3.1,4.1 –5 points / 2,5 points 5. Execution of laboratory task - PH 1.1 -5 points / 2.5 points 6. Modular test 3 - PH 1.2, 1.3, 2.1, 2.3 - 40 points / 20 points - final assessment: in the form of a credit

Ukrainian