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Molecular biology of viruses

Вибіркова дисципліна для ОП

First

2022/2023

8 Semester

3

PR06. Apply models, methods and data of physics, chemistry, ecology, mathematics in the process of learning and ensuring professional activity. PR07. To have techniques of self-education and self-improvement. Be able to project the trajectory of professional growth and personal development, applying the acquired knowledge. PR08. Know and understand the basic terms, concepts, theories and laws in the field of biological sciences and at the border of subject areas. PR11. Understand the structural organization of biological systems at the molecular level. PR13. Know the mechanisms of preservation, implementation and transmission of genetic information and their importance in evolutionary processes.

Full-time form

1. Know the theoretical foundations of virology, biochemistry, molecular biology, genetics. 2. Be able to independently apply knowledge of general virology, biochemistry, molecular biology, genetics.

The course "Molecular Biology of Viruses" covers the molecular aspects of replication strategies of viruses, including strategies for virus penetration into the cell, genome expression, assembly, release of DNA and RNA-containing viruses. Much attention is paid to key aspects of the interaction of viral and cellular components and their interaction on the end result of viral infections, unique mechanisms of antiviral cellular protection and viral response systems. Modern experimental approaches to the study of molecular mechanisms of virus reproduction and host-virus interactions are studied. Understanding the molecular mechanisms of virus-host interaction opens wide opportunities in the development of tools for the prevention and treatment of viral infections.

1. Андрійчук О.М., Коротєєва Г.В., Молчанець О.В., Харіна А.В. Вірусні інфекції людини та тварин: епідеміологія, патогенез, особливості противірусного імунітету, терапія та профілактика / КНУ імені Тараса Шевченка ВПЦ «Київський університет», 2014 р.-415с. 2. Вірусологія. Навчальний посібник для лабораторних занять / В.П. Поліщук, І.Г. Будзанівська, Т.П. Шевченко, О.М. Андрійчук, Т.А. Компанець, О.А. Кондратюк, Г.В. Коротєєва, О.В. Молчанець, А.В. Харіна, О.В. Шевченко. – К.: ЦП «Компринт», 2017. – 242 с. 3. Будзанівська І.Г. та ін. Вірусологія.-К., Київський університет, 2020.-347с. 4. Харіна А.В., Будзанівська І.Г., Поліщук В.П. Хіміотерапія вірусних інфекцій.-К.: Фітосоціоцентр.- 2003. 117 с. 5. Flint S.J., Enquist L.W., Krug R. M. Et al. Princirles of virology: molecular biology, pathogenesis, and control.- Washington, D.C.:ASM Press.- 2000. 6. Virus taxonomy. Classification and nomenklature of viruses. Ed. By M.H.V. van Regenmortel- Acad Press.- 2000.- 1147pp.

Lecture, individual work

Semester assessment: 1. Modular test 1 - PH 1.1 - 2.2 - 30 points / 15 points 2. Modular test work 2 - PH 1.1 - 2.2-30 points / 15 points 3. Oral answers / additions - RN 1.1 - 2.2 - 20 points / 10 points 4. Report RN 3.1 - 20 points / 10 points - final assessment: in the form of a test

Ukrainian