Infopaket

Cytopathology of viral infections

Вибіркова дисципліна для ОП

First

2022/2023

8 Semester

3

PR07. To have techniques of self-education and self-improvement. Be able to project the trajectory of professional growth and personal development, applying the acquired knowledge. PR08. Know and understand the basic terms, concepts, theories and laws in the field of biological sciences and at the border of subject areas. PR11. Understand the structural organization of biological systems at the molecular level. PR12. Demonstrate knowledge of the structure, life processes and functions of living organisms, understand the mechanisms of regulation of physiological functions to maintain the homeostasis of biological systems. PR14. To analyze the interactions of living organisms of different levels of phylogenetic relationship with each other, the peculiarities of the influence of various factors on living organisms and to evaluate their role in the biosphere processes of transformation of substances and energy.

Full-time form

1. Successful mastering of courses "Cytology", "Histology", "Biochemistry of viruses", "Virology", "General Genetics". 2. Be able to independently apply knowledge of cytology, histology, biochemistry, etc. disciplines, work with scientific and methodological literature. 3. Have basic skills in working with electron microscopic images of cells and cellular organelles, analyze their changes in viral infections.

Cell - a structural and functional unit of living things first responds to the penetration and reproduction of viruses. The infected cell undergoes changes in metabolic processes, in particular changes in membrane permeability to substrates and products of enzymatic processes, both in the cytoplasm and organelles, induces the synthesis of antigens. Penetrating into the cell, viruses cause various changes in the cell as a whole and its structural components. These changes primarily affect the structure and function of the plasma membrane and membrane compartments, namely - the nucleus, mitochondria; chloroplasts (in plant cells), peroxisomes, endoplasmic reticulum, Golgi apparatus and cytosol. Therefore, as a result of the interaction of cells and viruses there is a complex a set of morphological and cytophysiological changes that are specific to a viral infection.

1. Вірусологія: підручник / І.Г. Будзанівська, Т.П. Шевченко, Г.В. Коротєєва, О.В. Молчанець, А.В. Харіна, Т.А. Компанець, О.М. Андрійчук, О.В. Шевченко, О.А. Кондратюк. – К.: ВПЦ «Київський університет», 2019. – 351 с. 2. Вірусологія. Навчальний посібник для лабораторних занять / В.П. Поліщук, І.Г. Будзанівська, Т.П. Шевченко, О.М. Андрійчук, Т.А. Компанець, О.А. Кондратюк, Г.В. Коротєєва, О.В. Молчанець, А.В. Харіна, О.В. Шевченко. – К.: ЦП «Компринт», 2017. – 242 с. 3. Viral Cytopathology. H.H.Malherbe, M. Strickland-Cholmley. CRC Press. 2018. 78 p. 4. Principles of virology. Molecular Biology, Pathogenesis and Control. S.J. Flint et. Al., ASM Press. Washington, D.C., 2000.- p.-803. 5. Cytopathology. Encyclopedia of Pathology. Schmitt F. (eds) Springer International Publishing AG.-2017. 547р.

Lecture, individual work

Semester assessment: 1. Modular test 1 - RN 1.1, 1.2, 2.1 (block of topics of Section 1) - 15 points / 7.5 points 2. Modular test work 2 - RN 1.3, 1.4, 2.2 (block of topics of Section 2) - 15 points / 7.5 points 3. Presentations / reports of RN 3.1 - 30 points / 15 points - final assessment: in the form of an exam

Ukrainian