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Biophysical principles of regulation of cellular processes

Вибіркова дисципліна для ОП

First

2022/2023

7 Semester

3

PR08. Know and understand basic terms, concepts, theories and laws in the field of biological sciences and on the border of subject areas. PR11. To understand the structural organization of biological systems on molecular level. PR24. Analyze physical and chemical properties and functional the role of biological macromolecules and molecular complexes living organisms, the nature of their interaction with ions, molecules and radicals, their structure and energetics of processes. PR29.1. Apply acquired theoretical and practical knowledge skills for planning and conducting scientific experiments in the field of biophysics.

Full-time form

Successful mastering of the courses "Biochemistry", "Physiology and Anatomy of Man and Animals", "Biophysics", "Molecular Biology".

The task of the discipline is to form students' ideas about molecular and cellular mechanisms of regulation of cell life processes. The basic principles of information transmission in the cell, the structure and features of the functioning of membrane and intracellular receptors, as well as ways of signal transmission and conversion are considered. The knowledge acquired as a result of studying the discipline can be applied in research in both related sciences and in interdisciplinary fields, as well as serve as a theoretical basis for disciplines in the field of medicine.

1. Wallace Marshall,Gerald Karp,Janet Iwasa Karp’s Cell and Molecular Biology: Concepts and experiments/ 8th Edition.- Wiley, 2016.- Chepter 15 Cell Signaling and Signal Transduction:Communication Between Cells.- P.617-661. 2. Anne Combedazou and Damien Ramel a,Stephanie Gayralb, Nathalie Colombiec, Anne Fougeratb, Muriel Laffargueb Small GTPases orchestrate cell-cell communication during collective cell movement// Small gtpases.- 2020.- V. 11.- N. 2.- P. 103–112: https://doi.org/10.1080/21541248.2017.1366965 3. Raphael Trenker, Natalia Jura Receptor tyrosine kinase activation: From the ligand perspective // Current Opinion in Cell Biology.- 2020.- V 63.- P. 174-185; https://doi.org/10.1016/j.ceb.2020.01.016

Lecture, individual work

Current evaluation / control: 1. Modular control work 1 - PH 1.1; PH 1.2 - 20 points / 10 points 2. Modular control work 2 - PH 1.3; PH 1.4 - 20 points / 10 points 3. Evaluation of abstracts and presentations and reports on the selected topic RN 2.1- 3.1 - 30 points / 15 points 4. Evaluation of oral answers and additions RN 1.1- 3.1 - 30 points / 15 points - final assessment: in the form of a test

Ukrainian