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Biophysics of muscle contraction and cellular mobility

Вибіркова дисципліна для ОП

First

2022/2023

7 Semester

3

PR20. Argue the choice of methods, algorithms planning and conducting field, laboratory, clinical and laboratory research, including mathematical methods and software for conducting research, processing and presentation of results. PR27.1. Possess (modern) basic biophysical skills methods in biological research. PR29.1. Apply the acquired theoretical knowledge and practical skills for planning and conducting scientific experiments in the field of biophysics.

Full-time form

1. Be able to independently apply knowledge of biophysics, molecular biology, human and animal physiology, work with scientific and methodological literature. 2. Have basic knowledge and skills in working with materials and equipment used in laboratory research.

It is a discipline that combines basic research with broad application computer technologies, physical methods, such as tensometry, biomechanics, electrophysiological methods. The task of the discipline is to provide an understanding of the use of the complex fundamental, applied sciences and software aimed at analysis data on the structure and function of muscles, in particular in the quantitative assessment of their function in depending on the condition of muscle tissue or the influence of the environment. As a result of training, students will receive modern theoretical ideas about the structure of muscles, various manifestations of mobility that lie in the basis of the existence of life and practical skills to assess the state of muscle tissue of different types.

1 Костюк П.Г., Зима В.Л., Магура Ш.С., Мірошниченко М.С., Шуба М.Ф. Біофізика. Київ: Видавництво “ВПЦ Київський університет”. 2008. 567 с. 2 Біохімічні властивості та регуляція Са2+ -транспортувальних систем мембранних структур гладеньком’язевих клітин. Наукова думка, 2016. 273 с. 3 Хома О.М. Динаміка скорочення ішемізованого камбалоподібного м’яза щура / О. М. Хома, Д. А. Заводовський, Д. Н. Ноздренко, О. В. Долгополов, М. С. Мірошниченко, О. П. Мотузюк // Фізіологічний журнал. - 2014. - Т. 60, № 1. - С. 34-40. - Режим доступу: http://nbuv.gov.ua/UJRN/Fiziol_2014_60_1_7 4 Prylutskyy YI, Vereshchaka IV, Maznychenko AV, Bulgakova NV, Gonchar OO, Kyzyma OA, Ritter U, Scharff P, Tomiak T, Nozdrenko DM, Mishchenko IV, Kostyukov AI. C60 fullerene as promising therapeutic agent for correcting and preventing skeletal muscle fatigue. J Nanobiotechnology. 2017 Jan 13;15(1):8. doi: 10.1186/s12951-016-0246-1. PMID: 28086894; PMCID: PMC5237293.

Lecture, individual work

current evaluation / control: 1. Modular control work 1 - RN 1.1, 1.1, 1.4. – 20 points/10 points 2. Modular control work 2 - RN 1.3 - 15 points/17.5 points 3. Intermediate testing - RN 2.1-2.2 - 15/7.5 points 4. Evaluation of the presentation / report, oral answers / additions - RN 1.1-1.4. and 3.1. – 10 points/5 points - final assessment: in the form of an exam

Ukrainian