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Phylogenetic analysis in microbiology

Вибіркова дисципліна для ОП

First

2022/2023

7 Semester

3

PR02. Apply modern information technologies, software and Internet resources for professional information support activity PR10. Know the basics of systematics, methods detection and identification of non-cellular forms life, prokaryote and eukaryote and apply them for solving specific biological problems. PR11. Understand structural organization biological systems at the molecular level. PR13. Know the mechanisms of preservation, implementation and transfer of genetic information and their significance in evolutionary processes. PR14. Analyze interactions of living organisms different levels of phylogenetic relatedness between itself, the peculiarities of the influence of various factors on living organisms and evaluate their role in biosphere processes of transformation of substances and energy

Full-time form

1. Know: basics of general microbiology, biochemistry, biophysics, genetics, molecular biology. 2. Be able to independently apply knowledge of general microbiology, biochemistry, biophysics, genetics, molecular biology. 3. Have basic skills in processing scientific literature, solving problems, working with materials and equipment used in the microbiological laboratory, the use of software.

The subject of the discipline is the phylogenetic relationships between microorganisms, their relationships with other phyla of the tree of life; methods and technologies for obtaining, comparing, analyzing, annotating gene and protein sequences; methods of phylogeny reconstruction based on individual sequences and whole genomes; molecular markers to establish bacterial phylogeny; horizontal gene transfer as a factor of species diversity of microorganisms; modern approaches to genome analysis and phylogeny reconstruction, characteristic of the post-omic era.

1. C. Bleidorn Phylogenomics. An Introduction. Springer International Publishing AG. 2017. 222 p. 2. Library of Congress Cataloging-in-Publication Data 3. Pevsner, J.Bioinformatics and functional genomics / Jonathan Pevsner.—Third edition. Wiley Blackwell, Singapoure. 1124 p. 4. Palsson B.O. Systems Biology. Constraint-based Reconstruction and Analysis. Cambridge University Press. - 2015. - 531 p. 5. Сиволоб, А. В. Молекулярна біологія. — К. : Видавничо-поліграфічний центр «Київський університет», 2008, 384 с. 6. Генетика / А. В. Сиволоб, С. Р. Рушковський, С. С. Кир'яченко та ін. ; за ред. А. В. Сиволоба, — К. : Видавничо-поліграфічний центр «Київський університет», 2008, 320 с. 7. .A. Oren and R. T. Papke Molecular Phylogeny of Microorganisms. Caister Academic Press. USA,2010. 220 p. 8. Birge E. A. Bacterial and Bacteriophage Genetics Fifth Edition. –NY.: Springer, 2006. – 577 pp.

Lecture, individual work

Semester assessment: 1. Modular test work from the 1st section: PH 1.1, 1.2, 1.3, 2.1, 2.2, 3.1 - 30 points / 15 points 2. Modular test work from the 2nd section of PH 1.4, 1.5, 2.3, 2.4, 3.1 - 24/12 points 3. Modular test work from the 3rd section of PH 1.4, 1.5, 2.3, 2.4, 3.1 - 20 points / 10 points 4. Current test of knowledge (short tests, 10 papers of 1.6 points) RN 1.1-3.1 - 16 points / 8 points 5. Report: PH 3.1 - 10 points / 5 points - final assessment: in the form of a test

Ukrainian