Infopaket

Human genetics

Вибіркова дисципліна для ОП

First

2022/2023

6 Semester

3

PR07. To have techniques of self-education and self-improvement. Be able to project the trajectory of professional growth and personal development, applying the acquired knowledge. PR08. Know and understand the basic terms, concepts, theories and laws in the field of biological sciences and at the border of subject areas. PR09. To comply with the provisions of biological ethics, rules of biological safety and biological protection in the process of training and professional activity. PR13. To know the mechanisms of preservation, implementation and transmission of genetic information and their importance in evolutionary processes. PR17. Understand the role of the evolutionary idea of the organic world.

Full-time form

1. Successful mastering of the courses "Molecular Biology", "General Genetics", "Human and Animal Physiology", "Immunology", "Biochemistry". 2. Knowledge of the theoretical foundations of chemistry, physics, molecular biology, biochemistry, general genetics, etc. disciplines, the ability to use theoretical knowledge of these disciplines to solve practical problems. 3. Possession of basic skills in working with scientific electronic databases in the scientific literature and the ability to system analysis.

"Human Genetics" covers the study of inheritance and variability of normal and pathological human traits. When studying the general aspects of attention is given to the shortcomings of human preferences as a genetic object, methods used in human genetics, human genome organization, patterns of inheritance of mendelian and multifactorial traits, selected issues of developmental genetics, genetics of behavior and intelligence, genetic aspects of evolution and distribution of Homo sapiens sapiens sapiens. In acquaintance with the basics of medical genetics, the classification of hereditary diseases, molecular mechanisms of pathological conditions in the manifestation of hereditary diseases, the basics of oncogenetics and genetics of mental illness are considered.

1. Speicher M.R., Antonarakis S.E., Motulsky A.G. Vogel and Motulsky’s Human Genetics. Problems and Approaches. – Berlin: Springer, 2010. 2. Taneri B. Human Genetics and Genomics - Wiley-VCH Verlag GmbH, 2020. 3. Сиволоб А.В., Рушковський С.Р., Кир'яченко С.С. та інш. Генетика: підручник. – К.: Видавничо-поліграфічний центр “Київський університет“, 2008 . 4. Strachan T., Read A. Human Molecular Genetics (5th ed.). - Garland Science, 2019 5. Lewis R. Human Genetics: Concepts and Applications (12Th ed.). – N-Y.: The McGraw−Hill Education, 2019 6. Cummings M.R. Human heredity – N-Y.: Brooks Cole pub, 2003. 7. Grody W., Korf B., Pyeritz R. Emery and Rimoin’s principles and practice of medical genetics and genomics. Clinical principles and applications. - Academic Press, 2019.

Lecture, individual work

Semester assessment: 1. Modular test work1: PH 1.1 - 2.4 - 20 points / 10 points (block of topics of Section 1) 2. Modular test work 2: PH 1.1 - 2.4-20 points / 10 points (block of topics of the Section 2) 3. Solving practical problems: RN 2.1 - 3.1 - 10 points / 5 points 4. Evaluation of additions, answers, reports, tasks: RN 1.1 - 3.1 - 10 points / 5 points - final assessment: in the form of an exam

Ukrainian