Infopaket

Structure and functions of biological membranes

Вибіркова дисципліна для ОП

First

2021/2022

7 Semester

3

PRO3. Use the theories and laws of mathematics, physics, chemistry and other sciences to solve the problems of modern biology. PRO4. Understand the basic terms, concepts, principles, theories and laws in the field of biological sciences and at the border of subject areas PRO7. Demonstrate knowledge of the structural organization of biological systems at the molecular level of organization. PRO8. Demonstrate knowledge of fundamental biological processes, structure and functions of living organisms. PR15. Apply methods of determining structural and functional characteristics of biological systems at different levels of the organization in professional activities. PR16. Choose methods, algorithms for planning and conducting field, laboratory, clinical and laboratory research, including mathematical methods and software for research, processing and presentation of results.

Full-time form

1. Successful completion of Bioorganic Chemistry, Biochemistry, Molecular Biology, Cytology, Biophysics courses. 2. Knowledge of the theoretical foundations of bioorganic chemistry and biochemistry of lipids, proteins and carbohydrates - the main structural components of biological membranes, principles of structure and functioning / membrane organelles (plasma membrane, endoplasmic reticulum, Golgi apparatus, nucleus, mitochondrion, peroxisome, lysosome), biochemistry of enzymes, the role of membrane receptors in the transmission of extracellular signals into the cell, types of intercellular contacts, understanding of the terms "reactive oxygen species", "antioxidant", "lipid peroxidation". 3. Mastering the skills of working with devices used in practical biochemistry.

The discipline "Structure and functions of biological membranes" acquaints students with modern views on the biochemical composition and molecular structure of the plasma membrane and membranes of intracellular organelles, with the features of the structure of specific membrane areas - lipid rafts and caveolae, with modern methods of isolation and research of individual biological membranes and their components , with the biochemical mechanisms by which membranes realize their functions (transport, receptor, formation of intercellular contacts), with the processes underlying free radical damage to biological membranes, as well as with the involvement of these cellular structures in the implementation of various forms of cell death.

1. Богач П.Г. Курский М.Д. Кучеренко Н.Е., Рыбальченко В.К. Структура и функции биологических мембран. — К., Вища школа, 1981. — 336 с. 2. Гонський Я.Л., Максимчук Т.П., Калинський М.Т. Біохімія людини. Тернопіль:"Укрмедкнига", 2002.- 744 с. 3. Губський О.І. Біологічна хімія. - Київ-Тернопіль: Укрмедкнига, 2000.- 508 с 4. Остапченко Л.І., Михайлик І.В. Біологічні мембрани: методи дослідження структури і функцій / навчальний посібник. - К.: Видавничо-поліграфічний центр ,,Київський університет". -2006.-215 с 5. Остапченко Л.І. Компанець ІВ. Синельник Т.Б. Біологічні мембрани та основи внутрішньоклітинної сигналізації: методи дослідження. - 448 с / 2017 р., електронне видання https://www. biology univ.kiev.ua/images/stories/Kafedry/Biochimiya/Biblioteka/Biol_membrany/Ostap chenko_Kompanets_Biol.membrany.pdf

Lectures, self-study

Semester assessment: 1. Modular control work 1 - PH1.1-1.2; 2.1-2.3 20 points/ 10 points 2. Modular control work 2-RN 1.3 - 1.5; 2.4 - 15 points/ 7.5 points 3. Current pH tests 1.1 - 1.5; 2.1 -2.4; 3.1 - 25 points/ 12.5 points. - final assessment: in the form of an exam

Ukrainian