Infopaket

Population genetics

Вибіркова дисципліна для ОП

Second

2025/2026

2 Semester

4

PR19.5. Apply modern specialized methods of molecular and population genetics, as well as genetic analysis. PR20.5. Develop a systematic approach to the analysis and interpretation of new findings on the organization and functioning of living systems at the molecular, cellular, organismal, and population levels, drawing on advanced knowledge acquired through professionally oriented practical courses.

Full-time form

1. Successful mastering of the courses "Genetics", "Genetic monitoring", "Genetic Analysis". 2. Knowledge of the theoretical foundations of mathematics, statistics, ecology and genetics. 3. Ability to independently apply knowledge of genetics, etc. disciplines, perform practical work, work with scientific literature.

The course "Population Genetics" is designed to provide an in-depth understanding of the mechanisms underlying the formation, maintenance, and evolution of the genetic structure of populations. It covers the theoretical foundations of population genetics, including mathematical models of allele frequency dynamics, Hardy–Weinberg equilibrium, and the effects of mutations, natural selection, genetic drift, migration, and other evolutionary factors. Particular attention is paid to modern methods for studying population diversity, ranging from classical approaches to molecular genetic and bioinformatics methods, including next-generation sequencing (NGS), SNP analysis, population structure analysis, and genogeography. The course develops the analytical thinking skills required to conduct population genetic research in biology, medicine, ecology, evolutionary genetics, and related fields.

1. Ayala, F.J. and Kiger, J.A. Modern Genetics. Hunan Science and Technology Press, 1988. - 629 р. 2. Kimura M. The Neutral Theory of Molecular Evolution. Cambridge University Press: Cambridge, UK. 1985.- 600 р. 3. Методичні вказівки до практичних занять з курсу «Генетика з основами популяційної генетики». Для студентів третього курсу ННЦ «Інститут біології» напряму екологія, охорона навколишнього середовища та збалансоване природо користування / Серга С.В., Проценко О.В., Ейнор Д., Демидов С.В., Козерецька І.А. – Київ: Фітосоціоцентр, 2015. – 60с. 4. Ewens, W.J. Mathematical Population Genetics (2nd ed.). New York: Springer. 2004 ISBN 978-0-387-20191-7. 5. Orr, H. A. "The population genetics of beneficial mutations". Philosophical Transactions of the Royal Society B: Biological Sciences. 2010.- 365 р. (1544): 1195–1201.

Lectures and practical work, independent work

- semester assessment: 1. Modular test work1: PH 1.1-1.2 - 20 points / 10 points 2. Modular test work 2: PH 1.2-1.3 - 20 points / 10 points 3. Practical works: PH 2.1, 2.2, 3.1 - 10 points / 5 points 4. Assessment of practical problem-solving, oral reports, presentations, and oral responses: PH 1.1 - 4.1 - 10 points / 5 points - final assessment in the form of an exam

Ukrainian