Infopaket

Oncogenetics

Вибіркова дисципліна для ОП

First

2024/2025

10 Semester

3

PR02. Apply modern information technologies, software and Internet resources for information support of professional activities. PR07. Possess methods of self-education and self-improvement. Be able to design a trajectory of professional growth and personal development, applying the acquired knowledge. PR08. Know and understand the basic terms, concepts, theories and laws in the field of biological sciences and at the border of subject areas. PR09. Adhere to the provisions of biological ethics, rules of biological safety and biological protection in the process of learning and professional activities. PR12. Demonstrate knowledge of the structure, vital processes and functions of living organisms, understand the mechanisms of regulation of physiological functions to maintain homeostasis of biological systems.

External form

Successful mastering of the courses "Genetics", "Molecular Biology", "Biochemistry", "Cytology", "Human Genetics", as well as acquaintance with selected sections of human physiology, theory of evolution. Knowledge of the theoretical foundations of chemistry, physics, molecular biology, cell biology, etc .; ability to use theoretical knowledge of these disciplines to solve practical problems. Possession of basic skills in working with scientific electronic databases, scientific literature and the ability to system analysis.

The subject of the discipline "Oncogenetics" is the genetic basis of susceptibility to cancer, molecular genetic mechanisms of initiation and progression of tumors. General ideas about oncological diseases, causes and mechanisms of cell transformation as a result of chemical, physical and biological carcinogens, the role of genotype in cancer are considered. Attention is paid to molecular genetic processes that are disrupted at different stages of cell malignancy, genetic control of angiogenesis and metastasis. The issues of cancer prevention and determination of individual risk of tumor formation are discussed.

1. Rushkovsky S.R. Oncogenetics. Lecture course. - Kyiv: NSC "Institute of Biology", 2013. 2. Bunz F. Principles of cancer genetics. – Springer Verlag, 2016. 3. Molecular and Cell Biology of Cancer// ed. by Fior R., Zilhão R. – Springer Verlag, 2019. 4. Bozzone D. Cancer genetics. – N-Y.: Infobase Publishing, Inc., 2007 5. Speicher M.R., Antonarakis S.E., Motulsky A.G. Vogel and Motulsky's Human Genetics. Problems and applications. – Berlin: Springer, 2010. 6. Sherbet G.V. Lakshmi M.S. Genetics of Cancer: Genes Associated with Cancer Invasion, Metastasis and Cell Proliferation. – Elsevier Ltd., 2007. 7. Pitot H.C. fundamentals of oncology. – N-Y.: Marcel Dekker, Inc., 2002.

Lectures, independent work

Semester assessment: 1. Modular test 1: PH 1.1, 1,2, 2.1 - 2 .5 (remotely) - 20 points / 10 points 2. Modular test work 2: PH 1.3 - 2.5 - 20 points / 10 points 3. Solving practical problems: PH 2.1 - 3.1 - 10 points / 5 points 4. Evaluation of additions, answers, abstract: PH 1.1 - 3.1 - 10 points / 5 points Final assessment: in the form of an exam

Ukrainian