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Phylogenetic analysis in microbiology

Вибіркова дисципліна для ОП

First

2023/2024

10 Semester

3

PR06. Apply the principles of taxonomy, methods of detection and identification of non-cellular life forms, prokaryotes and eukaryotes. PR07. Demonstrate knowledge of the structural organization of biological systems at the molecular level of the organization. PR09. Demonstrate knowledge of heredity and variability, molecular mechanisms of conservation and realization of genetic information and importance in evolutionary processes. PR10. To establish regularities of interaction of living organisms of different forms of structural organization with each other, features of influence of various factors on living organisms and to estimate their role in biosphere processes of biotic transformation of substances and energy. PR13. Analyze the data of biological science

External form

1. Know: basics of general microbiology, biochemistry, biophysics, genetics, molecular biology. 2. Be able to independently apply knowledge of general microbiology, biochemistry, biophysics, genetics, molecular biology. 3. Have basic skills in processing scientific literature, solving problems, working with materials and equipment used in the microbiological laboratory, the use of software.

The subject of the discipline is the phylogenetic relationships between microorganisms, their relationships with other phyla of the tree of life; methods and technologies for obtaining, comparing, analyzing, annotating gene and protein sequences; methods of phylogeny reconstruction based on individual sequences and whole genomes; molecular markers to establish bacterial phylogeny; horizontal gene transfer as a factor of species diversity of microorganisms; modern approaches to genome analysis and phylogeny reconstruction, characteristic of the post-omic era.

1. C. Bleidorn Phylogenomics. An introduction. Springer International Publishing AG. 2017. 222 p. 2. Palsson B.O. systems biology. Constraint-based Reconstruction and Analysis. Cambridge University Press. - 2015. - 531 p. 3. Sivolob, A.V. Molecular biology. - K .: Publishing and printing center "Kyiv University", 2008, 384 p. 4. Genetics / A. V. Sivolob, S. R. Rushkovsky, S. S. Kiryachenko et al.; ed. A. V. Sivoloba, - K .: Publishing and Printing Center "Kyiv University", 2008, 320 p.

Lecture, independent work

Semester assessment: 1. Modular test work from the 1st section (remotely): PH 1.1, 1.2, 1.3, 2.1, 2.2, 3.1 - 30 points / 15 points 2. Modular test work from the 2nd section (remotely) PH 1.4, 1.5, 2.3, 2.4, 3.1 - 30 points / 15 points 3. Final modular test PH 1.1–1.5, 2.1– 2.4, 3.1 - 30 points / 15 points 4. Summary: PH 3.1 - 10 points / 5 points Final assessment: in the form of a credit

Ukrainian