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Structure and functions of peptides and proteins

Вибіркова дисципліна для ОП

First

2023/2024

6 Semester

3

PR03. Plan, execute, analyze data and present to study the results of experimental studies in ha- fields of biology. PR05. Demonstrate skills in evaluating unpredictable biological problems and deliberate choice of paths their solution. PR06. Apply models, methods and data of physics, chemistry, ecology, mathematics in the process of education and provision professional activity. PR08. Know and understand the main terms, concepts, theories ries and laws in the field of biological sciences and on the border of subject- them industries. PR11. To understand the structural organization of biological systems stem at the molecular level. PR20. Argue the choice of methods, algorithms of pla- organization and conduct of field, laboratory, clinical laboratory research, including mathematical methods and software for carrying out investigation, processing and presentation of results.

Full-time form

1. Successful mastering of the academic disciplines "Bioorganic Chemistry", "Biochemistry", "General on cytology", "Biochemistry", "Molecular biology", "Biophysics". 2. The ability to independently apply knowledge of bioorganic chemistry, general cytology, molecular biology, biochemistry, etc. academic disciplines to solve specific problems educational and practical tasks; to work with scientific and scientific methodical literature. 3. Mastery of basic system analysis skills.

The course "Structure and functions of peptides and proteins" introduces students to modern principles of structure, classification, physicochemical properties and biological functions of proteins and peptides. Particular attention is paid to the most important characteristics of amino acids, which make them unique structural elements of all living proteins. The concepts of the levels of structural organization of protein molecules, the domain principle of their construction and the fundamentality of the meaning and functions of proteins, which are directly determined by their structure, are also provided. The concept of folding, its dynamics and control mechanisms are considered. The discipline presents modern ideas about the classification of proteins, as well as prospects for the study, production and use of proteins and peptides in pharmaceuticals and various industries.

1. Garrett, R., Grisham, C. and Sabat, M. Biochemistry. – Boston, USA: Cengage Learning. – 2017. –863p. 2. D. L. Nelson, M.M. Cox Lehninger Principles of Biochemistry. - New York: W.Y.Freeman and Comp; 8-th edition- 2021- 1248p. 3. Остапченко Л.І., Андрійчук. Т.Р., Рибальченко В.К. та ін. Біохімія - Підручник для студентів ВНЗ. — Київ : Київський університет, 2016. — 798. 4. Марченко М.М., Худа Л.В., Великий М.М., Остапченко Л.І. Біохімія ензимів. – Чернівці: Чернівецький національний університет, 2012. – 416 с. 5. D. L. Nelson, M.M. Cox Lehninger Principles of Biochemistry. - New York:W.Y.Freeman and Comp.- 2005- 1119p. 6. Fersht, Alan. Structure and Mechanism in Protein Science: A Guide to Enzyme Catalysis and Protein Folding. Kaissa Publications. Kindle Edition. D.E.MetzlerBiochemistry. Thechemicalreactionsof living cells.-Acad. Press.- 2003 - 1950p.

Lecture, individual work

Semester assessment: 1. Modular test 1 - PH 1.1 - 1.5 - 20 points / 10 points 2. Modular test work 2 - PH 1.6 - 1.9 - 20 points / 10 points 3. Modular control work C - PH 2.1 - 2.3- 3.1 - 10 points / 5 points 4. Tests - RN 1.1 - 1.9, 2.1 - 2.3, 10 points / 5 points - final assessment: in the form of an exam

Ukrainian