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Modern medical chemistry

ВБ.4.04

Вибіркова дисципліна для ОП

Second

2023/2024

2 Semester

3

P1. Knowledge to understand scientific concepts and modern theories of chemistry, as well as the fundamentals of related sciences. P2. Deeply understand the basic facts, concepts, principles and theories related to the subject area mastered during the master's program, use them to solve complex problems and problems, as well as conduct research in the relevant field of chemistry. P3. Apply the acquired knowledge and understanding to solve new qualitative and quantitative problems of chemistry. Р08. To know principles and procedures of physical, chemical, physicochemical research methods, typical equipment, and instruments. P13. Analyze scientific problems and propose their solutions on an abstract level by decomposing them into components that can be investigated separately.

Full-time form

1. Know organic chemistry at the bachelor's degree in Chemistry. 2. Have an idea of the basic principles of molecular biology.

Research of the chemical mechanism of action of drugs at the molecular level, as well as the development (design) and synthesis of drugs. Chemistry of natural medicinal substances (structure research, synthesis, analysis). Approaches to drug development, mechanisms of penetration of exogenous substances into the human body, their reception by the cell, and signal transduction of the ligand with provocation of the effect.

1. Kovtunenko V.O. Drugs with an effect on the central nervous system. – Kyiv-Irpin, Perun publishing house, 1997. – 462 p. 2. Kovtunenko V.O. Drugs with an effect on the peripheral nervous system. – Kyiv, "Treo-plus" publishing house, 2005. – 426 p. 3. Kovtunenko V.O. Selected sections of neurochemistry, 2019. – 147 p. (on-line) 4. Wermuth C G. The practice of medicinal chemistry, 4rd ed. – Amsterdam/Boston: Elsevier. – 2015. 5. Patrick G. L. An introduction to medicinal chemistry, 6th ed. – Oxford: Oxford University Press. – 2017.

Lectures

Evaluation is carried out on a 100-point system. The maximum / minimum number of points that can be obtained by a student during the semester assessment is 100 points / 60 points. Current control - homework, tests (maximum 100 points)

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