Infopaket

Neurobiochemistry

ДВС.1.03.01

Вибіркова дисципліна для ОП

Second

2023/2024

3 Semester

4

The ability to build adequate models of chemical phenomena, to study them for obtaining new conclusions and deepening of understanding of nature, including using methods molecular, mathematical and computer modeling. Ability to organize, plan and implement a chemical experiment. The ability to interpret, objectively evaluate and present the results of one's work research. The ability to formulate new hypotheses and scientific problems in the field of chemistry, to choose directions and appropriate methods for their solution based on an understanding of modern issues research in the field of chemistry and taking into account the available resources. The ability to choose optimal research methods and techniques. Possession of the general methodology of carrying out scientific research.

Full-time form

1. Possession of scientific-theoretical and practical material of educational disciplines, which are taught to students of the "Bachelor" educational level. 2. Be able to independently and correctly approach research tasks apply knowledge of general physiology, anatomy, biochemistry, biophysics, etc. discipline, perform laboratory and practical work, have a good command of methods statistical analysis, work with scientific and methodical literature. 3. Have basic skills of working with materials and equipment, which are used in biological laboratories.

The subject of the academic discipline is the process of synaptic transmission in the brain; glutamate GABA-ergic neurotransmission; the role of the structural organization of the membrane and lipid-protein interactions in the regulation of the process of nerve impulse transmission; the role of presynaptic receptors in the regulation of key stages of the neurotransmission process and path determination modulation of the neurotransmitter reception system; molecular mechanisms of membranotropic action and neuroactive drugs; a potential peripheral marker for the analysis of disorders transport of neurotransmitters in the brain; environmental neurotoxicology; nanoneurotoxicology.

1.Bhagavan N.V., Chung-Eun Ha. Essentials of Medical Biochemistry 2th edition, Academic Press, 2011 2.Borisova T, Nazarova A, Dekaliuk M, Krisanova N, Pozdnyakova N, Borysov A, Sivko R, Demchenko AP. 3. Neuromodulatory properties of fluorescent carbon dots: Effect on exocytotic release, uptake and ambient level of glutamate and GABA in brain nerve terminals.// Int J Biochem Cell Biol. -2015.-V.59-P.203-15. 4.Blanco A., Blanco G. Medical Biochemistry, 2017 Elsevier Academic Press, 805. 5.Byrne J.H., Heidelberger R., Waxham M.N. FROM MOLECULES TO NETWORKS. An Introduction to Cellular and Molecular Neuroscience. THIRD EDITION / Elsevier Inc., 2014. - 692 р. 6. Lodish H., Berk A., Kaiser C.A., Krieger M., Bretscher A., Ploegh H., Amon A., Scott M.P. MOLECULAR CELL BIOLOGY. SEVENTH EDITION / W. H. Freeman and Company, New York, 2013. - 1247 р. 7. Pollard Т., Earnshaw W., Lippincott-Schwartz J., Johnso G. Cell Biology. 3rd Edition / Elsevier, 2017. - 882 р.

lectures, practical

- semester assessment: 1. Modular control work 1 – RN 1.1; 1.2. – 10 points/ 5 points 2. Modular control work 2 - RN 1.3; 1.4 – 10 points/ 5 points 3. Practical classes - RN 2.1; 2.2; 3.1 – 30 points/15 points 4. Evaluating the abstract of RN 4.1 – 10 points/ 5 points - final evaluation: in the form of an exam - 40 points

Ukrainian