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Modern chemistry of peptides and proteins

ВКБ.9.09

Вибіркова дисципліна для ОП

First

2022/2023

8 Semester

3

Р01. Knowledge to understand key chemical concepts, essential facts, concepts, principles, and theories relating to natural sciences... Р05. Knowledge to understand the relationship between structure and properties of substances. Р11. Skill to describe properties of aliphatic, aromatic, heterocyclic, and organometallic compounds, to explain nature and behavior of functional groups in organic molecules. Р12. To know main synthesis pathways in organic chemistry, including f interconversion of functional group and formation of carbon-carbon, carbon-heteroatom bonds. Р18. Ability to demonstrate knowledge and understanding of main facts, concepts, principles, and theories in chemistry. Р21. Ability to monitor and analyze scientific sources of information and professional literature.

Full-time form

1. Know the basic concepts of organic chemistry. 2. Be able to draw formulas of organic compounds. 3. Have basic skills in writing organic reactions. 4. Have basic knowledge of general chemistry. 5. Have an idea of the basics of organic chemistry within the course program "Organic Chemistry"

Finding of amino acids, peptides and proteins in natural objects, their extraction, chemical and biosynthesis, structure, physical, chemical and individual biological properties and practical application. Chemical and physicochemical properties of amino acids. Analysis of the chemical composition and amino acid sequence of peptides and proteins. Modern methods of synthesis of peptides and proteins. Modern physicochemical methods for establishing the spatial structure of peptides and proteins. Structure and functions of enzymes.

1. Pyvovarenko V.G. Fundamentals of bioorganic chemistry. – Kyiv: "Osvita", 1995. – 195 p. 2. Volovenko Yu.M., Kovtunenko V.O. Polymer level of matter organization. – K.: VOC "Kyiv University", 2013. – 335 p. 3. Sewald N., Jakubke H.-D. Peptides: Chemistry and Biology. – Wiley-VCH Verlag GmbH & Co, 2002. – 553 p. 4. Branden C., Tooze J. Introduction to protein structure. – N.-Y.: Garland Publishing inc., 1998. – 425 p.

Lectures and practical exercises

Semester control includes homework and tests. The evaluation is based on a 100-point scale. The maximum / minimum number of points that can be obtained by a student during the semester assessment is 60 points / 36 points. The final assessment is conducted in the form of an exam. The maximum / minimum number of points that can be obtained by a student in the exam is 40 points / 24 points.

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