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Molecular mechanisms of cell differentiation

Вибіркова дисципліна для ОП

Second

2021/2022

2 Semester

5

PR2. Use libraries, information databases, Internet resources to search for the necessary information. PR4. Solve complex problems in the field of biology, generate and evaluate ideas. PR7. Describe and analyze the principles of structural and functional organization, mechanisms of regulation and adaptation of organisms to the influence of various factors. PR8. Apply during research knowledge of the peculiarities of the development of modern biological science, the basic methodological principles of scientific research, methodological and methodological tools for conducting research for specialization. PR9. Plan research, choose effective research methods and ïx logistics.

External form

1. Successful mastering of academic disciplines taught to students of the educational level "Bachelor". 2. Knowledge of the theoretical foundations of molecular biology, biochemistry, genetics, cytology, embryology, cell biology. 3. Ability to independently apply knowledge of the above disciplines, perform laboratory and practical work, work with scientific literature and electronic databases, predict and critically evaluate research results, ability to system analysis.

The discipline "Molecular mechanism of cell differentiation" is a component of the educational program of professional training of specialists of educational level. "Master". The course is devoted to the study of molecular mechanisms of cell determination and differentiation at different stages of embryo development. Molecular mechanisms that control these processes are considered, special attention is paid to the regulation of gene expression during cell differentiation. The role of intercellular communications in the regulation of cell determination and differentiation is outlined. Examples of genetic diseases and anomalies associated with disruption of cell differentiation control systems are given. Methods of cell differentiation analysis and modern directions of research of this problem are demonstrated, the range of perspective projects in this field is outlined.

1. Sivolob A.V., Rushkovsky S.R., Kiryachenko S.S., Afanas'eva K.S. etc. Genetics. - M.: Kyiv University. - 2008 2. Alberts B., Johnson A., Lewis J., Raff M., Roberts K., Walter P. Molecular Biology of the Cell. Fifth Edition - New York, Garland Science, 2007. 3. Moody S.A. principles of developmental genetics. - Elsevier, 2007.

Lectures, practical work, independent work.

1. Modular test 1 (remote): PH 1.1 - 2.3, 4.1 - 30 points / 15 points 2. Modular test work 2: PH 1.1 - 2.3 - 20 points / 10 points 3. Final modular test - PH 1.1 - 3.1 - 40 points / 20. 4. Practical works: PH 2.1 - 4.1 - 10 points / 5 points. - final assessment: in the form of a credit

Ukrainian