Biochemical mechanisms of cell damage

Course: BIOLOGY (Master) PART-TIME

Structural unit: Biology And Medicine Institute Science Educational Center

Title
Biochemical mechanisms of cell damage
Code
Module type
Вибіркова дисципліна для ОП
Educational cycle
Second
Year of study when the component is delivered
2021/2022
Semester/trimester when the component is delivered
2 Semester
Number of ECTS credits allocated
5
Learning outcomes
PR04. Solve complex problems in the field of biology, generate and evaluate ideas. PR06. Analyze biological phenomena and processes at the molecular, cellular, organismal, population-species and biosphere levels in terms of basic general scientific knowledge, as well as using special modern research methods. PR07. Describe and analyze the principles of structural and functional organization, mechanisms of regulation and adaptation of organisms to the influence of various factors. PR08. Apply during research knowledge of the peculiarities of the development of modern biological science, the basic methodological principles of scientific research PR16. Critically comprehend theories, principles, methods in various fields of biology to solve practical problems and problems. PR19. Solve scientific-theoretical, research and applied problems of biology by appropriate methods.
Form of study
External form
Prerequisites and co-requisites
Successful mastering of scientific-theoretical and practical material of academic disciplines taught to students of EL "Bachelor". 2. Be able to independently apply knowledge of molecular biology, biochemistry, microbiology, etc. disciplines, perform laboratory and practical work, work with scientific and methodological literature. 3. Have basic skills in working with materials and equipment used in biological and biotechnological laboratories.
Course content
"Biochemical mechanisms of cell damage" - a discipline aimed at studying the mechanisms of response to damaging stimuli of various etiologies at the molecular and biochemical levels. The classification, types and principles of action of pathological stimuli on cells are considered. Particular attention is paid to the various stages of development of programmed cell death, the structure and functions of major regulators and mediators involved in the development of stress response in different cell types.
Recommended or required reading and other learning resources/tools
Berg, J. M., Timoshko, J. L. & Strier, L. Biochemistra. Freeman, 7th edition, 2011. Lodish, H., Burke, A., Zhipursky, S. L., Matsudaira, P., Baltimore, D. and James Darnell, J. Molecular Cell Biology, Freeman, 7th edition 2013. Nelson, DL & Cox, MM Lehninger Principles of Biochemistry. Freeman, 6th edition, 2013. Ryter, S. W., Cloonan, S. M. & Choi, A. M. Autophagy: critical regulator of cellular metabolism and homeostasis. Mol. Cells 36, 7-16 (2013). Choi, A. M., Ryter, S. W. & Levine, B. Autophagy in human health and disease. N. Engl. J. Med. 368, 651-662 (2013). Yuan, J. & Kroemer, G. Alternative cell death mechanisms in development and beyond. Gene Dev. 24, 2592-2602 (2010). Galluzzi, L., Kepp, O., Krautwald, S., Kroemer, G. & Linkermann, A. Molecular mechanisms of regulated necrosis. Semin. celldev. Biol. 35, 24-32 (2014).
Planned learning activities and teaching methods
Lectures, practical classes, independent work.
Assessment methods and criteria
1. Modular test 1 (remote) - PH 1.1; 1.2. - 20 points / 10 points 2. Modular test work 2 (remote) - PH 1.3; 1.4 - 20 points / 10 points 4. Minutes of practical classes / conclusions - PH 2.1 - 14 points / 7 points 5. Test (testing) PH 4.1 - 6 points / 3 points - final assessment: in the form of an exam
Language of instruction
Ukrainian

Lecturers

This discipline is taught by the following teachers

Dmytro Mykolaiovych Grebinyk
Department of Biochemistry
Biology And Medicine Institute Science Educational Center

Departments

The following departments are involved in teaching the above discipline

Department of Biochemistry
Biology And Medicine Institute Science Educational Center