Infopaket

Regulation of metabolism

Вибіркова дисципліна для ОП

Second

2021/2022

2 Semester

5

PR4. Solve complex problems in the field of biology, generate and evaluate ideas. PR6. Analyze biological phenomena and processes at the molecular, cellular, organismal, population-species and biosphere levels in terms of basic general scientific knowledge, as well as using special modern research methods. PR7. Describe and analyze the principles of structural and functional organization, mechanisms of regulation and adaptation of organisms to the influence of various factors. PR12. Use innovative approaches to solve complex problems of biology under uncertain conditions and requirements. PR19. Solve scientific-theoretical, research and applied problems of biology by appropriate methods. PR41. Be able to use existing and develop new methodological approaches, methods and algorithms for the analysis of biological systems at the molecular level of their organization, in the norm and in pathology, when changing the physiological status of the system.

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Successful mastering of courses Organic Chemistry, Biochemistry, Biophysics, Molecular Biology. Knowledge of the theoretical foundations of bioorganic chemistry and biochemistry of lipids, proteins and carbohydrates, biochemistry of enzymes. Possession of skills in working with devices used in practical biochemistry and molecular biology, calculating concentrations and making solutions.

The course acquaints the student with the molecular mechanisms of the main signaling cascades of the cell (adenylate cyclase, guanylate cyclase, phosphoinositide), with the peculiarities of intracellular signaling with the participation of reactive oxygen species, gas transmitters (NO, CO and H2S), inositol; highlights the role of phosphorylation and dephosphorylation of tyrosine residues in the regulation of protein functions; special attention is paid to the molecular mechanisms of signaling pathways initiated in the cell in response to the appearance of pathogens (signaling involving interferon).

Babenyuk Yu.D., Ostapchenko L.I., Skopenko E.V. Biochemistry: terms and nomenclature of enzymes: Textbook. - K .: Publishing and printing center "Kyiv University", 2005. - 356 p. Gonsky YAL., Maksimchuk T.P., Kalinsky M.I. Human biochemistry. Ternopil: "Ukrmedkniga", 2002. - 744 p. Gubsky Yu.I. Biological chemistry. - Kyiv-Ternopil: Ukrmedkniga, 2000.- 508 p. Ostapchenko L.I., Skopenko E.V. Biochemistry in schemes and tables: Textbook. - K .: Publishing and printing center "Kyiv University", 2004. - 128 p.

Lectures, practical classes, independent work.

1. Modular test 1 (remote) - PH 1.1, 1.2, 2.1, 4.1 - 20 points / 10 points 2. Modular test 2 (remote) - PH 1.3 - 1.5, 2.1, 4.1 - 20 points / 10 points 3. Final modular control work - PH 1.1. - 4.1. - 20 points / 10 points - final assessment: in the form of an exam

Ukrainian