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Biochemistry of macromolecular compounds

Вибіркова дисципліна для ОП

Second

2021/2022

2 Semester

5

PR02. Use libraries, information databases, Internet resources to search for the necessary information. PR04. Solve complex problems in the field of biology, generate and evaluate ideas. PR08. Apply during research knowledge of the peculiarities of the development of modern biological science, the basic methodological principles of scientific research, methodological and methodological tools for conducting research in specialization. PR16. Critically comprehend theories, principles, methods in various fields of biology to solve practical problems and problems. PR19. Solve scientific-theoretical, research and applied problems of biology by appropriate methods. PR21. Be able to use existing, develop and implement new research methods and technologies to solve a specific scientific-theoretical and / or applied problem in biochemistry.

External form

1. Successful mastering of scientific-theoretical and practical material of academic disciplines taught to students of EP "Bachelor". 2. Be able to independently apply knowledge of molecular biology, biochemistry, microbiology, etc. disciplines, perform laboratory and practical work, work with scientific and methodological literature. 3. Have basic skills in working with materials and equipment used in biological and biochemical laboratories.

"Biochemistry of macromolecular compounds" is a discipline that considers a range of issues related primarily to the structural organization and biochemical role of complexes of macromolecular nature. These complexes provide the passage and regulation of the vast majority of cell life at the molecular level: activation of enzymes and other protein factors, biosynthesis and catabolism of certain substances, generation and control of intracellular transduction signals and responses to external stimuli (hormones, growth factors, other physiological and as well as pathological factors, etc.), mediate the response to adverse conditions - the impact of pathogenic factors, nutrient deficiencies, induction of inflammation and various types of cell death.

Berg, J. M., Timoshko, J. L. & Strier, L. Biochemistra. Freeman, 7th edition, 2011. Lodish, H., Burke, A., Zhipursky, S. L., Matsudaira, P., Baltimore, D. and James Darnell, J. Molecular Cell Biology, Freeman, 7th edition 2013. Nelson, DL & Cox, MM Lehninger Principles of Biochemistry. Freeman, 6th edition, 2013. Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K. and Walter P. Molecular Biology of the Cell. Garland Science, 6th edition 2014. Karp, G. Cell Biology. Wiley, 7th edition 2013. Ryter, S. W., Cloonan, S. M. & Choi, A. M. Autophagy: critical regulator of cellular metabolism and homeostasis. Mol. Cells 36, 7-16 (2013). Choi, A. M., Ryter, S. W. & Levine, B. Autophagy in human health and disease. N. Engl. J. Med. 368, 651-662 (2013).

Lectures, independent work, practical classes.

1. Modular test 1 (remote) - PH 1.1; 1.2. - 20 points / 10 points 2. Modular test work 2 (remote) - PH 1.3; 1.4 - 20 points / 10 points 3. Minutes of practical classes / conclusions - PH 2.1 - 14 points / 7 points 4. Test (testing) PH 4.1 - 6 points / 3 points - final assessment: in the form of an exam

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