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Histophysiology of the neuroendocrine system

Вибіркова дисципліна для ОП

Second

2021/2022

2 Semester

5

PR2. Use libraries, information databases, Internet resources to search for the necessary information. PR6. Analyze biological phenomena and processes at the molecular, cellular, organismal, population-species and biosphere levels in terms of basic general scientific knowledge, as well as using special modern research methods. PR7. Describe and analyze the principles of structural and functional organization, mechanisms of regulation and adaptation of organisms to the influence of various factors PR11. To carry out statistical processing, analysis and generalization of the received experimental data with use of software and modern information technologies. PR 19. Solve scientific-theoretical, research and applied problems of biology by appropriate methods. PR 37. Be able to use modern methods of cytological and histological analysis to determine the physiological status of cells and / or tissues in normal and pathology, at different stages of ontogenesis and histogenesis.

External form

1. Know the histogenesis and submicroscopic structure of the elements of the glandular epithelium, anatomy, basics of biochemistry and physiology of endocrine organs. 2. Be able to use microscopic instruments to distinguish between different types of glandular cells of the endocrine system at the cyto- and histological level. 3. To have basic skills of making histological preparation of endocrine organs and the ability to work with a light microscope.

The learning process compares the main stages of the evolution of the neurosecretory system in invertebrates and vertebrates. Cytoarchitectonics of mammalian and human hypothalamus with characteristics of neurosecretory nuclei, hypothalamic tracts, medial elevation and pituitary gland, features of the structure of the portal circulatory system between the hypothalamus and pituitary gland are analyzed in detail. The histostructure of endocrine glands and the reasons for the development of the most common pathologies, features of morpho- and pathogenesis of endocrine glands and their consequences for the hormonal status of the organism are studied. Pierce's concept of the APUD system on the example of the characteristics of gastrointestinal endocrinocytes is considered.

1. Endocrinology. Textbook / Ed. A.S. Efimov. - K .: Higher School, 2004. - 494 p. 2. Endocrinology. Textbook / Ed. P.M. Bodor. - Vinnitsa: New Book, 2007. - 344 p. 3. Ostapchenko L.I. Hormonal regulation of metabolism and functions in the body. - K .: VPTs "Kyiv University", 2003. - 154 p.

Lecture, independent work, laboratory classes.

- semester assessment: 1. Modular control work (remote) PH 1.1. - 2. 2. - 20 points / 10 points. 2. Assessment of knowledge of histological preparations of the neuroendocrine system of the hypothalamus, pituitary gland, pineal gland and peripheral endocrine glands (checked by the teacher with a light microscope and oral description of the histological structure of the drug) PH 2.1 - 3.1 - 20 points / 10 points. 3. Laboratory works (2 works): PH 2.1, 2.2, 4.1 - 20 points / 10 points for each. - final assessment: in the form of an exam

Ukrainian