Infopaket

Mechanisms of virus persistence

Вибіркова дисципліна для ОП

Second

2021/2022

2 Semester

5

PR1. Know the state and foreign languages ​​at a level sufficient for communication on professional issues and presentation of the results of their own research. PR7. Describe and analyze the principles of structural and functional organization, mechanisms of regulation and adaptation of organisms to the influence of various factors. PR15. Be able to independently plan and perform an innovative task and formulate conclusions based on its results. PR20. On the basis of in-depth knowledge of natural sciences to form an idea of ​​the laws of individual and historical development of biological systems at different levels of organization, the role of systemic processes in their formation, functioning and plasticity, features of their cooperative interaction. PR36. Be able to form a system of analysis of the development of emergent and persistent infections and mechanisms of endogenization of viruses based on in-depth knowledge of the disciplines of vocational training.

External form

1. Successful mastering of the disciplines "Virology", "Principles of safety in the virology laboratory", "Virus identification", "Virus genetics", "Fundamentals of viral carcinogenesis", "Antiviral immunity", "Human and animal viruses". 2. Be able to independently apply knowledge of general virology and other disciplines to solve specific scientific and practical problems, work with scientific and scientific literature. 3. Have basic skills in developing recommendations for the prevention and control of this disease, the formation of a forecast of the spread of the disease under study

The course is a free choice of the student (choice of blocks) in the specialization "Virology" covers the system of knowledge and skills in the formation and development of persistent infection, the role of the immune system in this process and mechanisms to avoid viruses protective reactions. An important place is given to the study of molecular biological properties of HIV and its impact on the pathogenesis of infection, the main measures of infection prevention and approaches to treatment and control of HIV, the mechanisms of changes in the infected organism and the ineffective immune response. The course is designed to summarize the student's perception of the impact of persistent infections on the human body to provide insight into current trends and directions of basic scientific and applied research in the field of public health for future career guidance.

1. Polishchuk V.P., Molchanets O.V., Koroteeva G.V. HIV/AIDS and a healthy lifestyle. Kiev. - 2008 2.Andreichuk O.M, G.V. Koroteeva, O.V. Molchanets, A.V. Kharina. Viral infections of humans and animals: epidemiology, pathogenesis, features of antiviral immunity, therapy and prevention. Tutorial. Kiev. - 2014. 3. Zaporozhyan V.M., Aryaev M.L. HIV infection and AIDS. - 2nd ed., revised. and additional - Kyiv. Health. -2004. 4.Alkami A., Koszinowski U.H. Viral mechanisms of immune evasion. // Immunology Today. – 2000.-Vol. 21 5.Lorenzo M.E., Ploegh H.L., Tirabassi R.S. Viral immune evasion strategies and underlying cell biology. // Seminar in Immunology. – 2001.v. thirteen.

Lecture, independent work, practical classes.

- semester assessment: 1. Modular control work 1 - PH 1.1; 2.1– 20 points / 10 points 2. Modular test work 2 - РН 1.2,1.3, 2.2– 20 points / 10 points 3. Presentations / reports, oral answers: PH 1.1-1.3 and PH 3.1, 4.1 - 10 points / 5 points. 4. Practical works PH 2.1-2.2— 10 points / 5 points. - final assessment: in the form of an exam

Ukrainian