Medical genetics

Course: BIOLOGY (Master) PART-TIME

Structural unit: Biology And Medicine Institute Science Educational Center

Title
Medical genetics
Code
Module type
Вибіркова дисципліна для ОП
Educational cycle
Second
Year of study when the component is delivered
2021/2022
Semester/trimester when the component is delivered
2 Semester
Number of ECTS credits allocated
5
Learning outcomes
PR4. Solve complex problems in the field of biology, generate and evaluate ideas. PP19. Solve scientific-theoretical, research and applied problems of biology by appropriate methods. PP29. Be able to use modern specialized methods of molecular and population genetics and genetic analysis.
Form of study
External form
Prerequisites and co-requisites
1. Successful mastering of the courses “Molecular Biology? "Immunology? “Virology”, • “General Genetics”, “Biochemistry”, “Human Genetics”, “Oncogenetics”, “Genomics”, “Eukaryotic Chromosomes”, “Chromatin Molecular Organization” and “Genome Instability”. 2. Knowledge of the theoretical foundations of chemistry, physics, molecular biology, cell biology, etc .; ability to use theoretical knowledge of these disciplines to solve practical problems. 3. Possession of basic skills in working with scientific electronic databases, scientific literature and the ability to system analysis.
Course content
Course covers the study of inheritance and variability of human pathological traits. The classification of hereditary diseases, molecular mechanisms of pathological conditions in the manifestation of chromosomal and genetic hereditary diseases are considered. Attention is paid to hereditary predisposition to sporadic diseases (cancer, mental, cardiovascular diseases, etc.). The connection of different polymorphic variants of the human genome with different pathological conditions is considered. General information on pharmacokinetics and pharmacodynamics of drugs, causes of individual sensitivity to drugs, genetic variants of drug transport and metabolism systems, pharmacological aspects of genetic variants of drug target molecules are considered. Problems of appointment of individual schemes of drug therapy depending on a genotype of the patient are discussed.
Recommended or required reading and other learning resources/tools
1. Medical genetics // ed. Grechanina O.Ya. – M.: Medicine, 2007. 2. Rushkovsky S.R. Pharmacogenetics. Kypc lectures. - Kyiv NSC "Institute of Biology", 2013. 3. Jorde L.D., Carey J.S., Bamshad M.J. Medical genetics, 5th Edition. – Elsevier, 2016. 4. Cxaxyn M.P. Pharmacogenetics. - Ternopil: Ukrmedkniga, 2002.
Planned learning activities and teaching methods
Lectures, laboratory work, independent work
Assessment methods and criteria
1. Modular control work (remote) 2. Modular test work 2 (remotely): 3. Evaluation of laboratory work. 4. Evaluation of additions, oral answers, presentations. - final assessment: in the form of an exam
Language of instruction
Ukrainian

Lecturers

This discipline is taught by the following teachers

Stanislav Rushkovsky
Department of General and Medical Genetics
Biology And Medicine Institute Science Educational Center

Departments

The following departments are involved in teaching the above discipline

Department of General and Medical Genetics
Biology And Medicine Institute Science Educational Center