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Cytogenetic basis of embryonic development

Вибіркова дисципліна для ОП

First

2021/2022

8 Semester

3

PR02. Identify the ability to communicate in a foreign language in dialogue with colleagues and target audience. PR04. Understand the basic terms, concepts, principles, theories and laws in the field of biological sciences and on the boundaries of subject areas. PR07. Demonstrate knowledge of the structural organization of biological systems at the molecular level of the organization. PR08. Demonstrate knowledge of fundamental biological processes, structure and functions of living organisms. PR09. Demonstrate knowledge of heredity and variability, molecular mechanisms of conservation and realization of genetic information and importance in evolutionary processes. PR15. Apply in professional activities methods for determining the structural and functional characteristics of biological systems at different levels of the organization.

Full-time form

1. Successful mastering of the disciplines "Cytology", "Biology of individual development", "Genetics", "Biochemistry", "Molecular Biology", "Genetics of ontogenesis". 2. Ability to independently apply cytological, embryological and genetic knowledge to solve specific scientific and practical problems; work with scientific and scientific-methodical literature. 3. Possession of basic skills of information retrieval in electronic databases, the ability to analyze information.

The discipline "Cytogenetic bases of embryonic development" is a component of the cycle of professional training of specialists of the educational level "Bachelor" in the educational program "Biology" (specialization "Reproductive Biology"). The discipline covers the principles of genetic diagnosis of diseases of the embryo, fetus. The study of the discipline provides the theoretical foundations of cytogenetics and molecular genetic analysis of various types of biological samples: blastomeres, trophoblasts, chorionic villi, placental cells, blood and more. Invasive and non-invasive methods of material collection and research (karyotyping, PCR, FISH-method, NGS) are demonstrated, which allow to detect genetic and chromosomal abnormalities.

1. Медична генетика: підручник / За ред. О.Я. Гречаніної, Р.В. Богатирьової, О.П. Волосовця. — К.: Медицина, 2007. 2. Пішак В.П., Мещишин І.Ф., Пішак О.В. Основи медичної генетики: підручник. — Чернівці, 2000. — 248 с. 3. Путінцева Г.Й. Медична генетика. — 2-ге вид., перероб. та доп. — К.: Медицина, 2008. — 392 с. 4. Саляк Н.О. Навчальний посібник з медичної генетики: навч. посіб. — К.: Медицина, 2008. — 144 с. 5. Сиволоб А.В., Рушковський С.Р., Кир’яченко С.С, Генетика. Підручник – К.: Видавничо-поліграфічний центр “Київський університет“, 2008. - 384 с. 6. Jenjaroenpun P, Kremenska Y, Nair VM, Kremenskoy M, Joseph B, Kurochkin IV. 2013. Characterization of RNA in exosomes secreted by human breast cancer cell lines using next-generation sequencing. PeerJ, 1, 201-203

Lecture, individual work

Semester assessment: 1. Modular test 1 - PH 1.1 - 2.3 (block Section 1) - 25 points / 13 points 2. Modular test work 2 - RN 1.1 - 2.3 (block Section 2) - 25 points / 13 points 3. Preparation of the presentation / report RN 4.1 –10 points / 5 points - final assessment: in the form of an exam

Ukrainian