Infopaket

Biochemistry of macromolecular compounds

Вибіркова дисципліна для ОП

Second

2021/2022

2 Semester

5

PR02. Use libraries, information databases, Internet resources to search for the necessary information PR04. Solve complex problems in the field of biology, generate and evaluate ideas PR08. Apply during research knowledge of the peculiarities of the development of modern biological science, the basic methodological principles of scientific research, methodological and methodological tools for conducting research in specialization PR18. Model objects and processes in living organisms and their components using mathematical methods and information technology PR19. Solve scientific-theoretical, research and applied problems of biology by appropriate methods PR21. Apply existing, develop and implement new research methods and technologies to solve a specific scientific, theoretical and / or applied problem in biochemistry

Full-time form

1. Successful mastering of scientific-theoretical and practical material of academic disciplines taught to students of PR "Bachelor". 2. Be able to independently apply knowledge of molecular biology, biochemistry, microbiology, etc. disciplines, perform laboratory and practical work, work with scientific and methodological literature. 3. Have basic skills in working with materials and equipment used in biological and biotechnological laboratories.

Biochemistry of macromolecular compounds is an academic discipline that considers a range of issues related primarily to the structural organization and biochemical role of complexes of macromolecular nature. These complexes provide the passage and regulation of the vast majority of cell life at the molecular level: activation of enzymes and other protein factors, biosynthesis and catabolism of certain substances, generation and control of intracellular transduction signals and responses to external stimuli (hormones, growth factors, other physiological and as well as pathological factors, etc.), mediate the response to adverse conditions - the impact of pathogenic factors, nutrient deficiencies, induction of inflammation and various types of cell death.

Berg, J. M., Tymoczko, J. L. and Stryer, L. Biochemistry. Freeman, 7th edition, 2011. Lodish, H., Berk, A., Zipursky, S. L., Matsudaira, P., Baltimore, D. and James Darnell, J. Molecular Cell Biology, Freeman, 7th edition 2013. Nelson, D. L. & Cox, M. M. Lehninger Principles of Biochemistry. Freeman, 6th edition, 2013. Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K. and Walter P. Molecular Biology of the Cell. Garland Science, 6th edition 2014. Karp, G. Cell Biology. Wiley, 7th edition 2013. Ryter, S. W., Cloonan, S. M. & Choi, A. M. Autophagy: a critical regulator of cellular metabolism and homeostasis. Mol. Cells 36, 7–16 (2013). Choi, A. M., Ryter, S. W. & Levine, B. Autophagy in human health and disease. N. Engl. J. Med. 368, 651–662 (2013). Khaminets, A., Behl, C. & Dikic, I. Ubiquitin-dependent and independent signals in selective autophagy. Trends Cell Biol. 26, 6–16 (2016).

Lecture, practical classes, seminars, independent work

1. Modular control work 1 - PH 1.1; 1.2. - 20 points / 10 points 2. Modular control work 2 - PH 1.3. - 20 points / 10 points 3. Protocol of practical work / conclusions - RN 2.1; 2.2; 2.3. - 6 points / 3 points 4. Reports and presentations - RN 3.1 - 6 points / 3 points 5. Test work RN 4.1 - 8 points / 4 points - final assessment: in the form of an exam

Ukrainian