Infopaket

Viruses as vector systems

Вибіркова дисципліна для ОП

Second

2021/2022

3 Semester

4

PR01. Know the state and foreign languages ​​at a level sufficient for communication on professional issues and presentation of the results of their own research. PR08. Apply during research knowledge of the peculiarities of the development of modern biological science, the basic methodological principles of scientific research, methodological and methodological tools for conducting research in specialization. PR09. Plan research, choose effective research methods and their material support. PR14. Adhere to the norms of academic integrity in the study and conduct of scientific activities, know the basic legal norms for the protection of intellectual property. PR18. Model objects and processes in living organisms and their components using mathematical methods and information technology.

Full-time form

1. Successful mastering of the courses "Virology", "Molecular Biology", "Biotechnology", "Genetics of Viruses" and "Molecular Biology of Viruses". 2. Ability to apply knowledge and skills in the field of virology and molecular genetics, acquired during previous training, to search and analyze the scientific literature. 3. Possession of skills of abstract thinking, analysis and synthesis.

The discipline covers the basic principles of using viruses, or their fragments, to transfer recombinant DNA into the appropriate cell. The discipline considers various approaches to the creation of vectors for cloning nucleic acids and obtaining recombinant proteins based on the genomes of viruses of microorganisms (bacteriophages), invertebrates and vertebrates and humans, including hybrid constructs (cosmids, phagemids, fazmids, bacmids, etc.) and features of their application, scientific and theoretical foundations of practical use of vectors based on human viruses for DNA therapy and DNA vaccination

1. Budzanovskaya IG, Shevchenko TP, Koroteeva GV etc. Virology: textbook - K .: VPC "Kyiv University", 2019. 2. Kompanets TA Viruses as vectors (a course of lectures for students of the Faculty of Biology). - Kyiv: Phytosocial Center, 2007. 3. Viral vectors for gene therapy: Methods and protocols / Ed. by Machida C.A. - New Jersey: Humana Press, 2003. 4. Viral vectors: basik science and gene therapy / Ed. by Cid-Arregui A., Garcia-Carranca. - Natick: Eaton publishing, 2000.

Lecture, practical classes, independent work

Semester assessment: 1. Modular test 1 - PH 1.1 - 10 points / 5 points 2. Modular test work 2 - PH 1.2, 2.1, 2.2 - 10 points / 5 points 3. Modular test 3 - PH 1.2, 1.3, 2.1, 2.3 - 10 points / 5 points 4. Presentations / oral answers / additions - РН 1.1,2.2, 3.1,4.1 –10 points / 5 points 5. Practical tasks - PH 1.1 -20 points / 10 points Final assessment: in the form of an exam

Ukrainian