Infopaket

Molecular modeling of new medicines

Вибіркова дисципліна для ОП

Second

2021/2022

3 Semester

5

PR01. Be able to perform a patent search, find and process the necessary scientific and technical information; independently apply for the invention. PR02. Know domestic and international copyright law. Be able to protect your intellectual property and avoid infringement of other people's intellectual property. PR03. Carry out technical and economic calculations of design decisions and analyze and evaluate their effectiveness, environmental and social consequences in the short and long term. PR04. Be able to choose and apply the most appropriate methods of mathematical modeling and optimization in the development of scientific and technical projects.

Full-time form

Successful mastering of courses of EL "Bachelor". Be able to independently apply knowledge of biochemistry, biotechnology, molecular biology, etc. disciplines, perform laboratory and practical work, work with scientific and methodological literature. Have basic skills in working with materials and equipment used in biological and biotechnological laboratories.

Today's biotechnological developments require fundamentally new approaches to obtaining targeted biotechnological products in the field of pharmacology and related fields. One of the promising approaches is the search and molecular design based on the modeling of innovative target biotechnological products that can be new drugs. The concept of methodological approaches to modeling and creation of such new biotechnological products is the subject of this course. Applying this approach allows you to create fundamentally new, potentially commercially attractive biotechnological products with specified target properties that can be implemented in the pharmacological segment of the modern economy.

1. Donald J. Abraham, David P. Rotella Burger's Medicinal Chemistry, Drug Discovery, and Development, 8 Volume Set, 6th Edition // John Wiley & Sons.- 2002. 2. Tari, Leslie W. Structure-Based Drug Discovery // Springer.- 2012 3. Kenneth M. Merz, Jr., Dagmar Ringe, Charles H. Reynolds, Drug Design: Structure- and Ligand-Based Approaches // Cambridge University Press.- 2010 4 Leach A.R. and Gillet V.J. Introduction to chemoinformatics. Revised Edition // Springer.- 2007

Lecture, practical classes, independent work

Semester assessment: 1. Modular test 1 - PH 1.1 - 20 points / 10 points 2. Modular test 2 - PH 1.2-1.3 - 20 points / 10 points 3. Report on practical work - PH 2.1-2.3 - 12 points / 6 points 4. Abstract - 8 points / 4 points Final assessment: in the form of an exam

Ukrainian