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Fundamentals of modern pharmacology

Вибіркова дисципліна для ОП

Second

2021/2022

2 Semester

5

PR 1. To speak the state and foreign languages ​​at a level sufficient for communication on professional issues and presentation of the results of their own research. PR 5. Analyze and evaluate the impact of biology on the development of society. PR 14. Adhere to the norms of academic integrity in the study and conduct of scientific activities, know the basic legal norms for the protection of intellectual property. PR 24. Be able to use professional knowledge and practical skills to solve research and practical problems in the field of biophysics and medical informatics.

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1. Successful mastering of scientific-theoretical and practical material of academic disciplines taught by students of educational level "Bachelor", in particular "Biochemistry", "Biophysics", "Physiology of man and animals", "Molecular biology", "General and molecular genetics" . 2. Be able to independently apply knowledge of molecular biology, biochemistry, biophysics, etc. disciplines, perform laboratory and practical work, work with scientific and scientific-methodical literature. 3. Have the skills to work with computers, materials and equipment used in biological laboratories, be able to conduct quantitative analysis of experimental results.

This elective course is devoted to the study of molecular and cellular mechanisms of action of pharmacological drugs of the main groups and the principles of pharmacological correction of pathological conditions. Quantitative aspects of ligand interaction with receptors, main mechanisms of action of pharmacological drugs at the level of cells, tissues, organs and organism pharmacodynamics), regularities of changes in their concentration, metabolic transformations and excretion (pharmacokinetics), features of their influence depending on human genotype ), as well as the mechanisms of action of drugs of major pharmacological groups on various functional systems of humans and animals under normal conditions and various pathological conditions.

1. Pharmacology (textbook) / Chekman I. S., Gorchakova N. O., Kazak L. I. and others; ed. I. S. Chekman. - Vinnitsa: New Book, 2011.- 800 p: ill. 2. Pharmacology (textbook) / Nekoval I.V., Kazanyuk T.V. - M.: Energoatomizdat, 2007. - 504 p. 3. Medical Pharmacology at a Glance, 8th Edition/Neil M.J. - Wiley - Blackwell, 2015. - 120 pp. 4. Rang & Dale's Pharmacology, 8th Edition / Rang H.P., Ritter J.M., Flower R.J., Henderson G. – Churchill Livingstone, 2015. – 776pp. 5 Alexander S.P. etal. (2019). The concise guide to Pharmacology 2019/20. British Journal of Pharmacology, Vol. 176, Issue S1 [ Electronic resource ] Access mode: https://bpspubs.onlinelibrary.wiley.com/toc/14765381/2019/176/S1 6. Craig C.R., Stitzel R.E. Modern Pharmacology with clinic applications. Lippincott Williams & Wilkins, 2003. - 832 pp.

Laboratory work, independent work.

-semester assessment: 1. Modular test 1 (remote) - PH 1.1; 1.2; 2.1 - 10 points / 5 points 2. Modular test work 2 (remote) - PH 1.3; 1.4; 2.2 - 10 points / 5 points 3. Final modular test - PH 1.1 - PH 4.1 - 20 points / 10 points 4. Evaluation of reports on laboratory work - PH 2.1; 2.2; 3.1 - 20 points / 10 points - final assessment: in the form of an exam

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