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Molecular basis of pathological conditions

Обов’язкова дисципліна для ОП

Second

2021/2022

1 Semester

5

PR4. Solve complex problems in the field of biology, generate and evaluate ideas. PR6. Analyze biological phenomena and processes at the molecular, cellular, organismal, population-species and biosphere levels in terms of basic general scientific knowledge, as well as using special modern research methods. PR7. Describe and analyze the principles of structural and functional organization, mechanisms of regulation and adaptation of organisms to the influence of various factors. PR13. Adhere to the basic rules of biological ethics, biosafety, biosecurity, assess the risks of the latest biological, biotechnological and biomedical methods and technologies, identify potentially dangerous organisms or production processes that may pose a threat of emergencies. PR16. Critically comprehend theories, principles, methods in various fields of biology to solve practical problems and problems.

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Successful mastering of courses Organic Chemistry, Biochemistry, Molecular Biology. Knowledge of the theoretical foundations of molecular biology, bioorganic and biochemistry. Possession of skills in working with devices used in biochemistry and molecular biology.

The discipline is basic for the acquisition of knowledge and skills in the system of professional training of educational level "master". The discipline is designed to form in applicants an idea of ​​the molecular basis of the development of pathological conditions caused by certain changes in metabolic processes in the body. Studying the fundamentals of the development of pathological conditions of various origins will allow students to gain some knowledge that can be used in research in biology, medicine, pharmacology, as well as in developing diagnostic criteria and methods, obtaining potential pharmacological drugs.

Pathophysiology: textbook / M.N. Zaiko, Yu.V. Be, G.M. Butenko, etc. - K. Medicine, 2010. - 704 p. Sivolob A.V. Molecular biology. - M.: VPC "Kyiv University", 2008. - 384 p. Alberts B., Johnson A., Lewis J., et al. Molecular biology of the cell. 6th edition. - Garland Science, 2014. - 1465 p. Lodish H., Burke A., Kaiser S. et al. Molecular Cell Biology. 8th edition. – NY: W.H. Freeman and Company. - 2016. - 1278 Cooper G. M. The Cell. A Molecular Approach. 8th edition. - NY: Oxford University Press. - 2019. - 813

Lecture Individual work Lab work

1. Modular test 1 (remote) - PH 1.1 - 1.2 - 20 points / 10 points 2. Modular test work 2 (remote) - PH 1.3 - 20 points / 10 points 3. Reports on laboratory work - PH 2.1; 3.1 - 10 points / 5 points. 4. Summary - PH 4.1 - 10 points / 5 points. - final assessment: in the form of an exam

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