Infopaket

Oncogenetics

Вибіркова дисципліна для ОП

First

2021/2022

7 Semester

3

PRO4. Understand the basic terms, concepts, principles, theories and laws in the field of biological sciences and on the boundaries of subject areas. PRO5. Use knowledge and demonstrate compliance with the provisions of biological ethics, biological safety and biological protection. PRO8. Demonstrate knowledge of fundamental biological processes, structure and functions of living organisms. PRO9. Demonstrate knowledge of heredity and variability, molecular mechanisms of conservation and realization of genetic information and importance in evolutionary processes. PR16. Choose methods, algorithms for planning and conducting field, laboratory, clinical and laboratory research, including mathematical methods and software for research, processing and presentation of results. PR17. Through self-study to master new knowledge and modern methods of experimental research to solve problems of biology.

Full-time form

1. Successful mastering of the courses "Genetics", "Molecular Biology", "Biochemistry", "Cytology", "Human Genetics", as well as acquaintance with selected sections of human physiology, theory of evolution. 2. Knowledge of the theoretical foundations of chemistry, physics, molecular biology, cell biology, etc .; ability to use theoretical knowledge of these disciplines to solve practical problems. 3. Possession of basic skills in working with scientific electronic databases, scientific literature and the ability to system analysis.

The subject of the discipline "Oncogenetics" is the genetic basis of predisposition to cancer, molecular genetic mechanisms of initiation and progression of tumors. General ideas about oncological diseases, causes and mechanisms of cell transformation as a result of chemical, physical and biological carcinogens, the role of genotype in cancer are considered. Attention is paid to molecular genetic processes that are disrupted at different stages of cell malignancy, genetic control of angiogenesis and metastasis. The issues of cancer prevention and determination of individual risk of tumor formation are discussed.

1. Рушковський С.Р. Онкогенетика. Курс лекцій. - Київ: ННЦ «Інститут біології», 2013. 2. Bunz F. Principles of cancer genetics. - Springer Verlag, 2016. 3. Weber G.F. Molecular mechanisms of cancer. - Springer Verlag, 2007. 4. Bozzone D. Cancer genetics. - N-Y.: Infobase Publishing, Inc., 2007 5. Molecular and Cell Biology of Cancer/ Fior R, Zilhao R. (eds.) - Springer International Publishing, 2019 6. Sherbet G.V. Lakshmi M.S. The Genetics of Cancer: Genes Associated with Cancer Invasion, Metastasis and Cell Proliferation. - Elsevier Ltd., 2007. 7. Cancer: principles and practice of oncology/ DeVita V.T., Lawrence T.S., Rosenberg S.A. (eds.) - Wolters Kluwer, 2019

Lecture, individual work

Semester assessment: 1. Modular control work1. RN 1.1 - 2.5-20 points / 10 points (block of topics of Section 1) 2. Modular test work 2: PH 1.1 - 2.5-20 points / 10 points (block of topics of Section 2) 3. Solving practical problems: RN 2.1 - 3.1 - 10 points / 5 points 4. Evaluation of additions, oral answers, abstract: RN 1.1 - 3.1 - 10 points / 5 points - final assessment: in the form of an exam

Ukrainian