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Cytopathology of viral infections

Вибіркова дисципліна для ОП

First

2021/2022

8 Semester

3

PR04. Understand the basic terms, concepts, principles, theories and laws in the field of biological sciences and on the boundaries of subject areas. PR07. Demonstrate knowledge of the structural organization of biological systems at the molecular level of the organization. PR08. Demonstrate knowledge of fundamental biological processes, structure and functions of living organisms. PR10. Establish patterns of interaction of the living organisms of different forms of structural organization among themselves, features of influence of various factors on living organisms and to estimate their role in biosphere processes of biotic transformation of substances and energy. PR17. Through self-study to master new knowledge and modern methods of experimental research to solve problems of biology. PR23.4 Apply basic knowledge, skills and abilities to detect and identify pathogens of viral diseases.

Full-time form

1. Successful mastering of courses "Cytology", "Histology", "Biochemistry of viruses", "Virology", "General Genetics". 2. Be able to independently apply knowledge of cytology, histology, biochemistry, etc. disciplines, work with scientific and methodological literature. 3. Have basic skills in working with electron microscopic images of cells and cellular organelles, analyze their changes in viral infections.

Cell - a structural and functional unit of living things first responds to the penetration and reproduction of viruses. The infected cell undergoes changes in metabolic processes, in particular changes in membrane permeability to substrates and products of enzymatic processes, both in the cytoplasm and organelles, induces the synthesis of antigens. Penetrating into the cell, viruses cause various changes in the cell as a whole and its structural components. These changes primarily affect the structure and function of the plasma membrane and membrane compartments, namely - the nucleus, mitochondria; chloroplasts (in plant cells), peroxisomes, endoplasmic reticulum, Golgi apparatus and cytosol. Therefore, as a result of the interaction of cells and viruses there is a complex a set of morphological and cytophysiological changes that are specific to a viral infection.

1. Вірусологія: підручник / І.Г. Будзанівська, Т.П. Шевченко, Г.В. Коротєєва, О.В. Молчанець, А.В. Харіна, Т.А. Компанець, О.М. Андрійчук, О.В. Шевченко, О.А. Кондратюк. – К.: ВПЦ «Київський університет», 2019. – 351 с. 2. Вірусологія. Навчальний посібник для лабораторних занять / В.П. Поліщук, І.Г. Будзанівська, Т.П. Шевченко, О.М. Андрійчук, Т.А. Компанець, О.А. Кондратюк, Г.В. Коротєєва, О.В. Молчанець, А.В. Харіна, О.В. Шевченко. – К.: ЦП «Компринт», 2017. – 242 с. 3. Поліщук В.П., Будзанівська І.Г., Рижук С.М. та інш. Моніторинг вірусних інфекцій рослин в біоценозах України. – К. , Фітосоціоцентр. -2011. – 219 с. 4. Поліщук В.П., Будзанівська І.Г., Шевченко Т.П. Посібник з практичних занять до курсу «Загальна вірусологія» . – Київ: Фітосоціоцентр. – 2005. – 204 с. 5. Дзержинский М.Е., Пазюк Л.М., Гарматина С.М. та ін.. Загальна цитологія та гістологія, Навч. посібник Вид. Київський університет. - 2011 р., 223 с.

Lecture, individual work

Semester assessment: 1. Modular test 1 - RN 1.1, 1.2, 2.1 (block of topics of Section 1) - 15 points / 7.5 points 2. Modular test work 2 - RN 1.3, 1.4, 2.2 (block of topics of Section 2) - 15 points / 7.5 points 3. Presentations / reports of RN 3.1 - 30 points / 15 points - final assessment: in the form of an exam

Ukrainian