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Fundamentals of viral carcinogenesis

Вибіркова дисципліна для ОП

First

2021/2022

7 Semester

3

PR04. Understand the basic terms, concepts, principles, theories and laws in the field of biological sciences and on the boundaries of subject areas. PR05. Use knowledge and demonstrate compliance with the provisions of biological ethics, biological safety and biological protection. PR08. Demonstrate knowledge of fundamental biological processes, structure and functions of living organisms. PR12. Demonstrate knowledge of the structure and functions of the immune system, cellular and molecular mechanisms of immune responses, their regulation, genetic control; types of immunity and methods of assessing the immune status of the organism. PR17. Through self-study to master new knowledge and modern methods of experimental research to solve problems of biology.

Full-time form

1. Successful mastering of scientific-theoretical and practical material of academic disciplines taught to students of educational level "Bachelor". 2. Knowledge of the theoretical foundations of virology, biochemistry, microbiology, genetics, cytology and histology, physiology, zoology, biophysics, etc. 3. To have basic skills of analytical evaluation of research results conducted in the fields of biology and virology to solve a specific scientific and practical problem.

The subject of study of the discipline are the causes, conditions and mechanisms of formation of the neoplastic process under the influence of oncogenic viruses. The course is designed to summarize the student's understanding of the mechanisms of viral carcinogenesis, the general properties of oncoviral proteins, which allow to understand the stages of cell transformation under the influence of viruses, as well as provide insights into current trends and directions of basic scientific and applied research. The discipline is designed to form a system of abilities and skills in molecular biology of viruses, criteria for conditions and assessment of cell permissiveness for the formation of malignant growth. The acquired knowledge can be used both in research of related sciences and in interdisciplinary projects and which require knowledge of this discipline.

1. Вірусологія. Навчальний посібник для лабораторних занять / В.П. Поліщук, І.Г. Будзанівська, Т.П. Шевченко, О.М. Андрійчук, Т.А. Компанець, О.А. Кондратюк, Г.В. Коротєєва, О.В. Молчанець, А.В. Харіна, О.В. Шевченко. – К.: ЦП «Компринт», 2017. – 242 с. 2. Вірусологія: підручник / І.Г. Будзанівська, Т.П. Шевченко, Г.В. Коротєєва, О.В. Молчанець, А.В. Харіна, Т.А. Компанець, О.М. Андрійчук, О.В. Шевченко, О.А. Кондратюк. – К.: ВПЦ «Київський університет», 2019. – 351 с. 3. Молчанець О.В. Основи вірусного канцерогенезу/курс лекцій. Київ,- видавництво Укр.фітосоціоцентр,- 2009.-115 с. 4. Flint et al. Principles of Virology, 4th edition, 2015 5. Kaufmann et al. The immune response to infection, 2011 6. Norkin. Virology. Molecular biology and pathogenesis, 2010 7. Mahy et al. Desk encyclopedia of human and medical virology, 2010 8. Cann. Principles of molecular virology, 4th edition, 2005.

Lecture, individual work

Semester assessment: 1. Modular control work 1 - PH 1.1; 1.2, 2.1– 20 points / 10 points 2. Modular control work 2 - PH 1.3; 1.4, 2.2 - 20 points / 10 points 3. Presentations / reports - RN 3.1 –10 points / 5 points 4. Oral answers / additions - PH 1.1. - 2.2. 3.1– 10 points / 5 points - final assessment: in the form of a test

Ukrainian