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Biophysics of membrane transport

Вибіркова дисципліна для ОП

Second

2021/2022

3 Semester

4

PR06. Analyze biological phenomena and processes at the molecular, cellular, organismal, population-species and biosphere levels in terms of basic general scientific knowledge, as well as using special modern research methods. PR12. Use innovative approaches to solve complex problems of biology under uncertain conditions and requirements. PR14. Adhere to the norms of academic integrity in the study and conduct of scientific activities, know the basic legal norms for the protection of intellectual property. PR20. On the basis of in-depth knowledge of natural sciences to form an idea of ​​the laws of individual and historical development of biological systems at different levels of organization, the role of systemic processes in their formation, functioning and plasticity, features of their cooperative interaction.

Full-time form

1. Successful mastering of bachelor's courses: "Biophysics", "Physiology and anatomy of man and animals", "Molecular biology", "Biochemistry", etc. 2. Know the theoretical and practical foundations of biophysical methods in biological research; 3. Possess basic skills of staging and conducting biophysical experiments; methods of processing and analysis of biological data.

The discipline "Biophysics of membrane transport" is a fundamental biophysical discipline that deals with the structure, function and principles of functioning transport systems of the body. The discipline is designed to generalize the idea of ​​molecular and biophysical mechanisms of membrane transport. Particular attention is paid to the mechanisms of transmembrane ion transport and cell electrogenesis. During the study of the discipline much attention is paid to the practical application of knowledge in this field to develop new ways of influencing transport processes and / or correction of pathological conditions associated with their dysfunction.

1. Kosterin SO, Kalchenko VI, Veklich TO, Babich LG, Shlikov SG Calixarenes as modulators of ATP hydrolase systems of smooth muscle cells. Kyiv, Scientific Opinion, 2019, 266 p. 2. Shuba JM Fundamentals of molecular physiology of ion channels, K .: Nauk. Dumka, 447 pp., 2010. 3. Shuba MF, Davidovskaya TL, Prylutsky YI, Zholos OV, Bogutskaya KI Electrobiophysics. K .: Phytosociocenter, 152 pp., 2002. 4. Veselovsky NS, Fedulova SA, Kostyuk PG Biophysics of a single synapse. K .: Naukova Dumka, 2004. 5. Weiss T.F. Cellular Biophysics, Vol. 1: Transport. Thomas Fischer Weiss, 693 p., 1996. 6. Hille B. Ion channels of excitable membranes, Sunderland, Massachusetts, USA, Sinauer Associates, Inc., 3rd Edition, 814 p., 2001.

Lectures, laboratory work, independent work

Semester assessment: 1. Modular test 1 - PH 1.1-1.2 - 15 points / 8 points 2. Modular test 2 - PH 1.3 - 15 points / 8 points 3. Evaluation of reports on the results of laboratory work - PH 2.1-3.1 - 25 points / 13 points 4. Intermediate testing - pH 1.1-1.3; 4.1 - 5 points / 3 points Final assessment: in the form of an exam

Ukrainian