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Immunochemistry

Вибіркова дисципліна для ОП

First

2021/2022

9 Semester

3

PR03. Use theories and laws of mathematics, physics, chemistry and other sciences to solve problems of modern biology. PR07. Demonstrate knowledge of the structural organization of biological systems at the molecular level of the organization. PR12. Demonstrate knowledge of the structure and functions of the immune system, cellular and molecular mechanisms of immune responses, their regulation, genetic control; types of immunity and methods of assessing the immune status of the organism. PR16. Choose methods, algorithms for planning and conducting field, laboratory, clinical and laboratory studies, including mathematical methods and software for research, processing and presentation of results. PR21.4. Apply immunological, physicochemical and immunochemical methods to study biological phenomena and processes.

External form

1. Successful mastering of scientific-theoretical and practical material of disciplines taught to students of educational level "Bachelor": "Physiology and anatomy of man and animals", "Immunology", "Microbiology", "Biochemistry", "Anatomy and morphology of the lymphoid system" etc. 2. Ability to independently apply knowledge of the basics of anatomy, histology and cytology, general immunology, physiology and biophysics, biochemistry and other disciplines to solve specific scientific and practical problems; work with scientific and scientific-methodical literature. 3. Possession of basic skills of systems analysis.

The course is devoted to the study of the structure and properties of antigens and antibodies, mechanisms and consequences of their interaction during the immune response and in immunochemical analysis. The discipline "Immunochemistry" covers the structure, classification and characteristics of antigens, structure, mechanism of immunoglobulin biosynthesis, synthesis and properties of antibodies of different isotopes, antigenic properties of antibodies. Antibody-dependent cellular and humoral immune responses are studied. Particular attention is paid to immunochemical analysis. A review of classical serological research methods, as well as immunochemical analysis of antigens and antibodies based on indirect registration of immune complexes: enzyme-linked immunosorbent assay, immunofluorescent and radioimmune. The principles of immunocytochemical, immunohistochemical analysis and immunochemical analysis of biological fluids are considered separately.

1. Immunology. Textbook. Vershigora AYu, Pasteur ES, Kolybo DV. etc. K.: Publishing and Printing Center "Kyiv University", 2011, 559p. 2. Jeneway CA, Travers P, Walport M, Shlomchik M Immunology: The immune system in health care and the faculty: 5 years: New York and London: Garland Publishing; 2002:732 3. Burmester GR, Pezzutto A. Color atlas of immunology. N.Y.: Thieme, 2007, 369 p. 4. Yakobysyak M. Immunology (textbook) / Edited by Chopyak V.V. (translation) // New Book. - Vinnitsa. - 2004. - 672 p. 5. Microbiology, virology, immunology / Sytnik I.A., Klimnyuk S.I., Tvorko M.S. 6. Fundamentals of immunology / Tvorko M.S., Klimnyuk S.I., Tkachuk N.I. - T .: Publishing house of medical university, - 2009. - 297p.

Lecture, independent work

Semester assessment: 1. Modular test 1 (remotely): PH 1.1 - 3.1 –20 / 10 points; 2. Modular test 2 (remotely): PH 1.1 - 3.1 - 20/10 points; 3. Modular test 3: PH 1.1- 3.1 - 20/10 points. Final assessment: in the form of an exam

Ukrainian