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Biochemistry of viruses

Вибіркова дисципліна для ОП

First

2021/2022

8 Semester

3

PR03. Use theories and laws of mathematics, physics, chemistry and other sciences to solve problems of modern biology. PR04. Understand the basic terms, concepts, principles, theories and laws in the field of biological sciences and interdisciplinary fields. PR07. Demonstrate knowledge of the structural organization of biological systems at the molecular level of the organization. PR17. Through self-study to master new knowledge and modern methods of experimental research to solve problems of biology. PR22.4. Based on information about the structural organization of the virus and the peculiarities of interaction with the cell, choose the best methods for its isolation, purification and concentration

External form

1. Successful mastering of courses "Biochemistry", "Biotechnology", "Virology", "Genetics". 2. Be able to independently apply knowledge of molecular biology, biochemistry, microbiology, etc. disciplines, work with scientific and methodological literature. 3. Have basic skills in classifying viruses in Baltimore.

An important place is given to the peculiarities of the structure of simple and complex viruses, types of virion symmetry, methods and phenomena discovered on viral proteins as models and their application in modern science. Much attention is paid to aspects of biochemical interaction of virus and cell and the role of proteins in virus penetration, regulatory and enzymatic properties of viral proteins, unique features of biochemical structure of viral nucleic acids as carriers of genetic information. The study of the biochemistry of viruses, as the basis of general and molecular virology, is relevant for the development of effective means of combating viral infections at different stages of the life cycle of viruses.

1. Budzanovskaya I.G. and others. Virology.-K., Kyiv University, 2020.-347p. 2. Structure and Physics of Viruses: An Integrated Textbook (Subcellular Biochemistry 68) 2013thEdition, Kindle Edition.- Springer; 2013th Edition (Jun 4, 2013).- 747p. 3. Virus Protein and Nucleoprotein Complexes (Subcellular Biochemistry Book 88) 1st ed. 2018Edition, Kindle Edition-Springer; 1st ed. 2018 Edition.- 442p. 4. Acheson N.H. Fundamentals of molecular virology.- John Wiley & Sons.- 2007.- 432pp. 5. Bacteriophage: Genetics and Molecular Biology. Eds.: McGrath S., van Sinderen D. - CaisterAcademic Press, 2007. -344 P. 6. Cann A.J. Principles of Molecular Virology. –Academic Press, London, 2001. – 234 p.

Lecture, independent work

Semester assessment: 1. Modular test 1 (remote) (MR1) (test): PH 1.1.-2.2 (Block of topics of Section 1-3) —50 points / 25 points. 2. Abstract PH 3.1 –10 points / 5 points Final assessment: in the form of an exam

Ukrainian