Infopaket

Molecular biophysics

Вибіркова дисципліна для ОП

First

2021/2022

7 Semester

3

PR03. Use theories and laws of mathematics, physics, chemistry and other sciences to solve problems of modern biology. PR04. Understand the basic terms, concepts, principles, theories and laws in the field of biological sciences and on the boundaries of subject areas. PR07. Demonstrate knowledge of the structural organization of biological systems at the molecular level of the organization. PR08. Demonstrate knowledge of fundamental biological processes, structure and functions of living organisms. PR15. Apply in professional activities methods for determining the structural and functional characteristics of biological systems at different levels of the organization. PR21. Solve applied problems of biology appropriate methods. PR23.1. Possess (modern) basic biophysical methods in biological research. PR24.1. Have modern methods of information technology in biology.

Full-time form

1. Successful mastering of scientific-theoretical and practical material of educational disciplines taught to students of educational level "Bachelor", in particular "Physics", "Chemistry", "Bioorganic Chemistry", "Biophysics", "Biochemistry", "Molecular Biology". 2. Be able to independently apply knowledge of biophysics, biochemistry, molecular biology and other disciplines, work with scientific and methodological literature. 3. Have the skills to work with computers, materials and equipment used in biological laboratories.

During the study of the course much attention is paid to modern ideas about the molecular structure, physicochemical properties and functioning of biological macromolecules of various natures. The main sections of the course are devoted to the general structural organization of biological macromolecules and their physicochemical properties, mechanisms of intermolecular interactions, conformational transitions, organization and functioning of supramolecular complexes, molecular mechanisms of cell signaling, and principles of research methods in molecular biophysics. In the future, the acquired knowledge and skills in the field of "Molecular Biophysics" can be used both in research in the field of biophysics and in interdisciplinary research.

1. Boal D. Mechanics of the Cell, 2nd Edition. - Cambridge University Press, 2012. – 608 pp. Режим доступу: http://www.sfu.ca/~boal/moc2.html 2. Zholos A. Studying endogenous TRP channels in visceral and vascular smooth muscles. In “TRP channels”, Methods in Signal Transduction Series. Editor M.X. Zhu, Boca Raton (FL): CRC Press, Taylor & Francis Group, 2011. - 499 pp. (Chapter 9, 195-218). Режим доступу: https://www.ncbi.nlm.nih.gov/books/NBK92812/ 3. Zaccai N.R., Serdyuk I.N., Zaccai J. Methods in Molecular Biophysics: Structure, Dynamics, Function for Biology and Medicine, 2nd Edition. – Cambridge University Press, 2017. – 702 pp. 4. Frauenfelder H., Chan S.S., Chan W.S. The Physics of Proteins: An Introduction to Biological Physics and Molecular Biophysics. – Springer, 2010. – 448 pp.

Lecture, individual work

Current evaluation / control: 1. Modular control work 1 - PH 1.1; 1.2. - 30 points / 15 points 2. Modular control work 2 - PH 1.3; 1.4– 30 points / 15 points 3. Presentation - PH 3.1 - 15 points / 8 points 4. Summary - RN 2.3 - 15 points / 8 points 4. Intermediate testing of pH 2.1; 2.2 - 10 points / 5 points - final assessment: in the form of a test

Ukrainian