Infopaket

Oncogenetics

Вибіркова дисципліна для ОП

Second

2025/2026

8 Semester

3

PR02. Understanding and knowledge of fundamental and clinical biomedical sciences, at a level sufficient for solving professional tasks in the field of health care. PR04. To identify and identify the leading clinical symptoms and syndromes (according to list 1); using standard methods, using preliminary data from the patient's history, patient examination data, knowledge about the person, his organs and systems, to establish a preliminary clinical diagnosis of the disease (according to list 2). (+ PRN 31, 32, 35)

1. Successful completion of the courses "Medical Biology", "Histology, Cytology and Embryology", "Biological and Bioorganic Chemistry", "Pathomorphology", as well as familiarization with selected sections of human physiology and pharmacology. 2. Knowledge of the theoretical foundations of chemistry, physics, molecular biology, cell biology, etc.; ability to use theoretical knowledge from these disciplines to solve practical problems. 3. Possession of elementary skills in working with scientific electronic databases, scientific literature and the ability to perform systematic analysis.

The subject of study of the discipline “Oncogenetics” is the genetic basis of predisposition to cancer diseases, molecular genetic mechanisms of initiation and progression of tumors. General ideas about oncological diseases, causes and mechanisms of cell transformation as a result of the action of chemical, physical and biological carcinogens, the role of genotype in carcinogenesis are considered. Attention is paid to molecular genetic processes that are disrupted at different stages of cell malignancy, genetic control of angiogenesis and metastasis. Issues of prevention and treatment of cancer diseases and determination of individual risk of tumor formation are discussed.

Основні: (Базові) 1. Bunz F. Principles of cancer genetics. - Springer Verlag, 2022. 2. Weber G.F. Molecular mechanisms of cancer. - Springer Verlag, 2007. 3. Bozzone D. Cancer genetics. - N-Y.: Infobase Publishing, Inc., 2007 4. Molecular and Cell Biology of Cancer/ Fior R, Zilhao R. (eds.) - Springer International Publishing, 2019 5. Sherbet G.V. Lakshmi M.S. The Genetics of Cancer: Genes Associated with Cancer Invasion, Metastasis and Cell Proliferation. - Elsevier Ltd., 2007. 6. Cancer: principles and practice of oncology/ DeVita V.T., Lawrence T.S., Rosenberg S.A. (eds.) - Wolters Kluwer, 2019

Modular test work, evaluation of oral answers, essays and additions, evaluation of solving research problems

semester assessment: 1. Modular test paper 1: РН 1.1 – 2 .5 – 30 points/15 points (block of topics of Section 1) 2. Modular test paper 2: РН 1.1 – 2.5 – 30 points/15 points (block of topics of Section 2) 3. Practical work: РН 1.1 – 3.1 – 30 points/15 points 4. Assessment of additions, essays, oral answers: РН 1.1 – 2.5 – 10 points/5 points - final assessment: in the form of a credit

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