Infopaket

Structural basis of protein and peptide function

Вибіркова дисципліна для ОП

First

2025/2026

9 Semester

3

PR06. Apply models, methods and data of physics, chemistry, ecology, mathematics in the process of learning and ensuring professional activity. PR08. Know and understand the basic terms, concepts, theories and laws in the field of biological sciences and at the border of subject areas. PR11. Understand the structural organization of biological systems at the molecular level. PR12. Demonstrate knowledge of the structure, vital processes and functions of living organisms, understand the mechanisms of regulation of physiological functions to maintain homeostasis of biological systems. PR24. Analyze the physicochemical properties and functional role of biological macromolecules and molecular complexes of living organisms, the nature of their interaction with ions, molecules and radicals, their structure and energetics of processes.

External form

1. Successful completion of the courses "Chemistry", "General Cytology", "Bioorganic Chemistry", "Biochemistry", "Molecular Biology", "Biophysics". 2. Be able to independently apply previously acquired knowledge in molecular biology, biochemistry, biophysics and other disciplines to solve specific scientific and practical problems; work with scientific and methodological literature, search for new scientific data, work with scientific and methodological literature 3. Possession of basic skills of systems analysis.

The academic discipline "Structural foundations of the functioning of proteins and peptides" includes the study of the features of the structure and functions of amino acids, peptides and proteins. Considerable attention is paid to the consideration of the primary, secondary, tertiary and quaternary structure of polypeptide molecules. The discipline covers the study of the features of the functioning of proteins, in particular, includes a discussion of the molecular mechanisms of catalysis of reactions by enzymes and the regulation of their activity. Common methods of modifying the polypeptide chain are studied, and the influence of these modifications on the features of the functioning of proteins.

1. G. C.IBarrett, D. T. Elmore Amino Acids and Peptides. – Cambridge university press. - 2004. – p.225. 2. David Whitford. Proteins: Structure and Function. - Wiley. - 2005. - p. 544. 3. Ivet Bahar, Robert L. Jernigan, Ken A. Dill Protein Actions: Principles and Modeling. - Garland Science . - 2017 . - 322 Pages. 4. D. L. Nelson, M.M. Cox Lehninger Principles of Biochemistry. - New York: W.Y.Freeman and Comp; 8-th edition- 2021- 1248p. 5. Garrett, R., Grisham, C. and Sabat, M. Biochemistry. – Boston, USA: Cengage Learning. – 2017. –863p.

Lectures, independent work

Semester assessment: 1. Modular test 1 (remotely) – RN 1.1-1.5 – 20 points 2. Modular test 2 – RN 1.6-2.3 – 30 points 3. Test - RN 3.1 – 10 points Summary assessment: in the form of an exam