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Basics of glycobiology

Вибіркова дисципліна для ОП

First

2025/2026

10 Semester

3

PR02. Apply modern information technologies, software and Internet resources for information support of professional activities. PR04. Communicate orally and in writing on professional issues using scientific terms accepted in the professional environment, in the state and foreign languages. PR07. Possess methods of self-education and self-improvement. Be able to design a trajectory of professional growth and personal development, applying the acquired knowledge. PR08. Know and understand the basic terms, concepts, theories and laws in the field of biological sciences and at the border of subject areas. PR12. Demonstrate knowledge of the structure, vital processes and functions of living organisms, understand the mechanisms of regulation of physiological functions to maintain homeostasis of biological

External form

1. Successful completion of the courses "Bioorganic Chemistry", "Biochemistry", "Molecular Biology". 2. Be able to independently apply previously acquired knowledge in molecular biology, biochemistry and other disciplines, search for new scientific data, work with scientific and methodological literature. 3. Possess elementary skills in working with materials and equipment used in biological and biotechnological laboratories.

"Fundamentals of Glycobiology" is an integral science that examines the main classes of carbohydrates, glycans, sialic acids, hyaluronates and carbohydrate-bound molecules. The structure of the main classes of the above-mentioned molecules is described, the main metabolic processes associated with glycans and carbohydrate-bound molecules, as well as their derivatives, are characterized, and the mechanisms of the development of pathologies that result from impaired synthesis or degradation are considered. This discipline highlights methods for diagnosing these diseases, protocols for their diagnosis and treatment. Demonstrates an analysis of modern challenges in science aimed at improving the diagnosis and treatment of congenital glycosylation diseases. Despite the fact that glycan molecules have a very complex structure and are still very difficult to synthesize and reproduce, this new field of research inspires great hopes for future results. The interaction of biochemistry, molecular biology, genetics, genetic engineering, microbiology, chemistry and chemical technology in the field of problematic issues of carbohydrate biochemistry leads to the creation of new means of diagnosis, prevention and treatment of the most common human diseases. The development of carbohydrate biochemistry is associated with the solution of one of the global problems of humanity - improving the state of health care and extending life expectancy.

1. Fundamentals of Glycobiology / Ed. N. Sibirna – Lviv: Ivan Franko National University, 2015. – 492 p. 2. Biochemistry: textbook / Ed. L.I. Ostapchenko – K.: Publishing and Printing Center “Kyiv University”, 2012. – 796 p. 3. Varki A., Cummings R.D., Esko J.D. et al. Essentials of Glycobiology, 4th edition. – Cold Spring Harbor Laboratory Press. – 2022. – 859 p. 4. Ostapchenko L.I., Rybalchenko V.K. “Biological and Bioorganic Chemistry” K: Publishing and Printing Center “Kyiv University”, 2015, 917 p. 5. Introduction to Glycobiology. Maureen E. Taylor and KurtDrickamer. Oxford University Press; 3rd edition; 2011.

Lectures, independent work

Semester assessment: 1. Modular test1 (remotely) RN 1.1 – 3.1– 30 points/ 15 points 2. Modular test2 RN 1.1 – 3.1– 30 points/ 15 points Summary assessment (semester control): in the form of an exam