Infopaket

Electrobiophysics and membrane biophysics

Вибіркова дисципліна для ОП

First

2025/2026

6 Semester

3

PR04. Communicate orally and in writing on professional issues using scientific terms adopted in the professional environment, in the state and foreign languages. PR08. Know and understand the basic terms, concepts, theories and laws in the field of biological sciences and on the border of subject areas. PR11. Understand the structural organization of biological systems at the molecular level. PR24. Analyze the physicochemical properties and the functional role of biological macromolecules and molecular complexes of living organisms, the nature of their interaction with ions, molecules and radicals, their structure and energetics of processes. PR28.1. Possess modern methods of information technology in biology

Full-time form

1. Successful mastery of scientific, theoretical and practical material of academic disciplines taught to students of the educational level "Bachelor", in particular "Biophysics", "Biochemistry", "Physiology and Anatomy of Humans and Animals", "Molecular Biology", "General Genetics". 2. Be able to independently apply knowledge of biophysics, biochemistry, molecular biology, genetics and other disciplines, work with scientific and methodological literature. 3. Have skills in working with a computer, materials and equipment used in biological laboratories

The subject of the academic discipline is the electrical properties of cells and tissues, physicochemical processes that underlie electrogenesis, in particular biophysical and molecular mechanisms of formation and maintenance of transmembrane ion gradients and transmembrane ion transport. The main electrophysiological methods for studying multicellular preparations and isolated cells, the principles of operation of modern robotic patch-clamp systems, the basic principles of classical biophysics of ion channels, molecular biophysics and physiology of ion channels, modern classification of potential- and ligand-gated ion channels and their numerical functions, biophysical and molecular mechanisms of calcium homeostasis and signaling are considered. In the future, the knowledge and skills acquired in the field of “Electrobiophysics and Biophysics of Membranes” can be applied both in scientific research in the field of biophysics and interdisciplinary research.

1. Шуба М.Ф., Давидовська Т.Л., Прилуцький Ю.І., Жолос О.В., Богуцька К.І. Електробіофізика. - К.: Фітосоціоцентр, 2002. - 152 с. 2. Давидовська Т.Л., Мірошниченко М.С., Прилуцький Ю.І., Жолос О.В. (2006). Теоретичні та експериментальні основи біофізики електричних явищ. К.: Фітосоціоцентр, 190 с. 3. Шуба Я. М. Основи молекулярної фізіології іонних каналів. - К. : Наук. Думка, 2010. – 447 c. 4. TRiPs across epithelial and endothelial barriers in health and disease. Editors A.V. Zholos, G.M. Tolstanova, Nova Science Publishers, New York. – 2021, 257 pp. 5. Hille B. Ion channels of excitable membranes, 3rd Edition. - Sunderland, Massachusetts, USA: Sinauer Associates, 2001. - 814 p. 6. Kandel E.R., Schawartz J.H., Jessel T.M., Siegelbaum S.A., Hudspeth A.J. Principals of neural science, 5th Edition. – The McGeaw-Hill Companies, Inc., 2013. – 1760 p.

Lectures, consultations, independent work

- ongoing assessment / control: 1. Modular test paper 1 – RN 1.1; 1.2. – 20 points/10 points 2. Modular test paper 2 – RN 1.3; 1.4– 20 points/10 points 3. Essay – RN 2.3 – 10 points/5 points 4. Presentation – RN 3.1 – 10 points/5 points - final assessment: in the form of an exam

Ukrainian