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Genetics of reproduction

Вибіркова дисципліна для ОП

Second

2025/2026

2 Semester

5

PR19.5. Apply modern specialized methods of molecular and population genetics, as well as genetic analysis. PR20.5. Develop a systematic approach to the analysis and interpretation of new findings on the organization and functioning of living systems at the molecular, cellular, organismal, and population levels, drawing on advanced knowledge acquired through professionally oriented practical courses.

Full-time form

1. Successful mastering of disciplines taught to students of the educational level "Bachelor". 2. Knowledge of the theoretical foundations of molecular biology, biochemistry, genetics, cytology, embryology, cell biology. 3. Ability to independently apply knowledge of the above disciplines, perform laboratory and practical work, work with scientific literature and electronic databases, predict and critically evaluate research results, ability to system analysis.

The course focuses on the genetic aspects of human reproductive health. The basics of human genetics, pathophysiological and molecular genetic mechanisms of their reproductive function are considered, special attention is paid to hypothalamic-pituitary-gonadal regulation of the human reproductive system, violation of sexual differentiation processes and genetic aspects of sex determination. Examples of genetic diseases and abnormalities associated with disruption of cell differentiation control systems at different stages of embryonic development of the male and female reproductive systems are given. The separate role of use of modern assisted reproductive technologies (DTR) in treatment of disturbance of reproductive function at the person is considered, their efficiency and prospects of the further development for the decision of problems of infertility are estimated.

1. Sivolob AV, Rushkovsky SR, Kiryachenko SS, Afanasieva KS etc. Genetics. - Kyiv: University of Kyiv. - 2008 2. Stéphane Viville, Karen D. Sermon Textbook of Human Reproductive Genetics. - Cambridge university press. – 2023. - p. 246. 3. SCOTT F. GILBERT Developmental Biology. Second Edition- Sunderland Ma - 1988 - 843р. 4. Цитогенетичні методи дослідження хромосом людини: метод. рекомендації / Міністерство охорони здоров'я України; уклад.: Зерова-Любимова Т.Е., Горовенко Н.Г. – Київ, 2003. – 25 с. 5. Оцінка токсинності та генотоксичності наночастинок Ag2S, синтезованих за допомогою біологічних матриць, на тест-системі Drosophila melanogaster Mg. (Diptera: Drosophilidae). Проценко О.В., Ясінський Я., Горюнова І.І…Пірко Н.М..// Фактори експериментальної еволюції організмів. – 2018. – Том 23. – С.114-119.

Lectures and practical work, independent work

- semester assessment: 1. Module control work 1: PH 1.1 - 2.3 - 20 points/10 points 2. Module control work 2 : PH 1.1 - 2.3 - 20 points/10 points 3. Evaluation of the presentation / report, oral answers / additions - PH 1.1 - 4.1 - 10 points / 5 points 4. Practical work: PH 2.1 - 3.1 - 10 points/5 points - Final assessment: in the form of an exam

Ukrainian