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Modern physicochemical methods in genetics

Вибіркова дисципліна для ОП

First

2025/2026

8 Semester

3

PR03. Plan, perform, analyze data and present the results of experimental research in the field of biology. PR07. Possess methods of self-education and self-improvement. Be able to design a trajectory of professional growth and personal development, applying the acquired knowledge. PR08. Know and understand the basic terms, concepts, theories and laws in the field of biological sciences and at the border of subject areas. PR11. Understand the structural organization of biological systems at the molecular level. PR19. Apply in practical activities methods for determining the structural and functional characteristics of biological systems at different levels of organization. PR20. Argue the choice of methods, algorithms for planning and conducting field, laboratory, clinical and laboratory research, including mathematical methods and software for conducting research, processing and presenting results.

External form

1. Successful completion of the courses "Physics", "General Genetics", "Molecular Biology", "Biochemistry", "Biophysics". 2. Knowledge of the theoretical foundations of chemistry, physics, genetics, biochemistry and biophysics. 3. Possession of elementary skills in working with laboratory equipment, the ability to perform laboratory and practical work, work with scientific literature. 4. Ability to work in Excel and Origin programs, skills in working with electronic databases.

The educational discipline "Modern physico-chemical methods in genetics" is a component of the educational program of professional training of specialists of the educational degree "Bachelor". The course is devoted to the study of the principles of modern physico-chemical methods of research and the peculiarities of their application in the analysis of biological macromolecules and interactions between them. The capabilities and limitations of the main physical and chemical methods, the principles of method selection in relation to the purpose of the research are demonstrated. The methods that can be applied in setting up experiments in related sciences and in the framework of interdisciplinary projects, and which require in-depth knowledge of the given discipline, are highlighted. Particular attention is paid to modern physicochemical methods used in the diagnosis and prognosis of genetic diseases in medical practice in Ukraine and the world. In the course of studying the discipline, the practical application and significance of certain methods in molecular and medical genetics are presented or demonstrated.

1. Afanasyeva K.S. Physical methods in molecular genetics. Practicum K.: "Kyiv University" Publishing Polygraphic Center, 2016, 127 p. 2. Afanasyeva K.S., Chopei M.I. Educational and methodological manual "Modern methods of molecular biology", Kyiv, 2024. - 129 p. 3. Ostapchenko L.I., Rybalchenko V.K. Biological and bioorganic chemistry. In 2 volumes - K.: Kyiv University Publishing and Printing Center, 2014, 1043 p. 4. Syvolob A.V. Molecular biology. - K.: Kyiv University Publishing and Printing Center, 2023. 5. Serdyuk I.R., Zaccai N.R., Zaccai J. Methods in molecular biophysics - Cambridge: Cambridge University Press, 2007, 1120 p.

Lectures, independent work

Semester assessment: 1. Modular tests 1 and 2 (one remote): RN 1.1 – 1.4, 2.3 – 50 points/25 points 2. Solution of research problems: RN 2.1 – 3.1 – 5 points/2.5 points 4. Evaluation of oral and written answers: RN 1.1 – 3.1 – 5 points/2.5 points Summary assessment: in the form of an exam

Ukrainian