Infopaket

Mechanisms of virus persistence

Вибіркова дисципліна для ОП

Second

2023/2024

3 Semester

5

PR01. To speak the state and foreign languages at a level sufficient to communicate on professional issues and present the results of their own research. PR07. To describe and analyze the principles of structural and functional organization, mechanisms of regulation and adaptation of organisms to the influence of various factors. PR17. Apply modern teaching technologies for teaching special disciplines. PR20. On the basis of in-depth knowledge of natural sciences to form an idea of the laws of individual and historical development of biological systems at different levels of organization, the role of system processes in their formation, functioning and plasticity, features of their cooperative interaction, as well as the systematic organization of life. PR36. To be able to form a system of analysis of the development of emergent and persistent infections and mechanisms of endogenization of viruses based on in-depth knowledge of professional training disciplines.

Full-time form

1. Successful mastering of the disciplines "Virology", "Principles of safety in the virology laboratory", "Virus identification", "Virus genetics", "Fundamentals of viral carcinogenesis", "Antiviral immunity", "Human and animal viruses". 2. Be able to independently apply knowledge of general virology and other disciplines to solve specific scientific and practical problems, work with scientific and scientific-methodological literature. 3. Have basic skills in developing recommendations for the prevention and control of this disease, the formation of a forecast of the spread of the disease under study.

The discipline "Mechanisms of virus persistence" is a free choice of the student (choice of blocks) in "Virology" covers the system of knowledge and skills in the formation and development of persistent infection, the role of the immune system in this process and mechanisms to avoid viruses. An important place is given to the study of molecular biological properties of HIV and its impact on the pathogenesis of infection, the main measures of infection prevention and approaches to treatment and control of HIV, the mechanisms of changes in the infected organism and the ineffective immune response. The course is designed to summarize the student's perception of the impact of persistent infections on the human body to provide insights into current trends and directions of basic scientific and applied research in the field of public health for future professional orientation.

1. Polishchuk VP, Molchanets OV, Koroteeva GV HIV / AIDS and a healthy lifestyle. Kyiv.- 2008 2. Andriychuk OM, GV Koroteeva, OV Molchanets, AV Harina. Viral infections in humans and animals: epidemiology, pathogenesis, features of antiviral immunity, therapy and prevention. Tutorial. Kyiv.- 2014. 3. Zaporozhyan VM, Aryaev ML HIV and AIDS. - 2nd ed., Reworked. and add.- Kyiv. Health. -2004. 4.Alkamі A., Koszinowski U.H. Viral mechanisms of immune evasion. // Immunology Today. - 2000.-Vol. 21 5. Lorenzo ME, Ploegh H.L., Tirabassi R.S. Viral immune evasion strategies and underlying cell biology. // Seminar in Immunology. - 2001. v. thirteen. 6. Zinkernagel R.M. Virus-induced immunopathology. || Viral Pathologesis and Immunity (edit. N.Nathanson) .- 2001.

Lectures, practical classes, independent work

- semester assessment: 1. Module control work 1 - PH 1.1; 2.1- 20 points / 10 points 2. Module control work 2 - PH 1.2, 1.3, 2.2- 20 points / 10 points 3. Presentations / reports, oral answers: WP 1.1-1.3 and WP 3.1, 4.1 - 10 points/5 points. 4. Practical work WP 2.1-2.2; 3.1- 10 points/5 points. - Final assessment: in the form of an exam

English