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Phylogenetic analysis

Вибіркова дисципліна для ОП

Second

2023/2024

2 Semester

5

PR2. Use libraries, information databases, and Internet resources to find the necessary information. PR4. Solve complex problems in the field of biology, generate and evaluate ideas. PR06. Analyze biological phenomena and processes at the molecular, cellular, organismal, population-species and biosphere levels in terms of fundamental general scientific knowledge, as well as using special modern research methods. PR11. Conduct statistical processing, analysis and generalization of experimental data using software and modern information technologies. PR30. To be able to form a system of analysis and interpretation of new results on the organization and functioning of living systems at the molecular, cellular, organismal and population levels based on in-depth knowledge of the disciplines of professional and practical training.

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1. Successful completion of the courses "Ecology", "Botany", "Zoology", "Molecular Biology", "Microbiology", "Virology", "General Genetics", "Bioinformatics". 2. be able to independently apply knowledge of molecular biology, genetics, botany, zoology and other disciplines, perform practical work, work with scientific and methodological literature. 3. Possess basic skills in working with computer programs and databases used to search and analyze features (DNA and protein sequences, morphological and ecological features of taxa, etc.)

Phylogenetic analysis is a modern approach to the study of the evolutionary history of organisms and their relationship to each other in many biological sciences (genetics, microbiology, virology, zoology, botany, etc.). As part of the Phylogenetic Analysis course, students have the opportunity to familiarize themselves with the theory and practice of phylogenetic analysis, master the skills of conducting it, and learn how to formulate an evolutionary scenario based on an existing phylogenetic tree. The discipline "Phylogenetic Analysis" is a part of the cycle of professional training of specialists of the master's degree, its theoretical core is formed by such sciences as the theory of evolution and statistical analysis. At the same time, it is closely related to such disciplines as biodiversity, systematics, bio- and phylogeography, evolutionary morphology, etc.

1. Kimura M. The Neutral Theory of Molecular Evolution. Cambridge University Press: Cambridge, UK. 1985.- 600 р. 2. Bioinformatics: a practical guide to the analysis of genes and proteins, 2nd Ed / A.D. Baxevanis, B.F.F. Ouellette. – New York: John Wiley & Sons, 2001. – 455 p. 3. Delsuc F., Brinkmann H., Philippe H. (2005). Phylogenomics and the reconstruction of the tree of life // Nat Rev Genet. – 2005. – Vol. 6 (5). – P. 361–375. doi:10.1038/nrg1603. 4. Mount D.W. Bioinformatics: Sequence and genome analysis. – Cold Spring Harbor Laboratory Press - 2001, 564 p. 5. The Phylogenetic Handbook/ Edited by P. Lemey, M. Sameli, A-M. Vandamme. – Cambridge: Cambridge University Press. – 2009, 723 p.

Lectures, laboratory work, independent work.

- semester assessment: 1. Module control work 1 - PH 1.1-1.3, 2.1, 2.2, 3.1, 4.1 - 20 points / 10 points 2. Module control work 2 - PH 1.1-1.3, 2.1, 2.2, 3.1, 4.1 - 20 points / 10 points 3. Module control work 3 - PH 1.1-1.3, 2.1, 2.2, 3.1, 4.1 - 20 points / 10 points 4. Report on the results of the individual work 1 - PH 1.1-1.3, 2.1, 2.2, 3.1, 4.1 - 10 points / 5 points 5. Laboratory work, evaluation of the report, report on practical work - PH 1.1-1.3, 2.1, 2.2, 3.1 - 4.1 - 30 points / 15 points - Final assessment: in the form of a test

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